University of Padua Medical School, Padua, Italy
Eur Heart J. 2015 Apr 7;36(14):837-46. doi: 10.1093/eurheartj/ehu493. Epub 2015 Jan 29.
Arrhythmogenic right ventricular cardiomyopathy is a recent discovery in the field of non-ischaemic myocardial diseases. It represents a unique example on how it is possible in few years to move from the identification of a new lethal morbid entity at the anatomical theatre towards the unveiling of the genetic aetiology, thus allowing early detection of carriers with effective strategies for premature death prevention.
致心律失常性右室心肌病是近年来非缺血性心肌疾病领域的一项新发现。它代表了一个独特的范例,即在短短几年内,人们从解剖学领域鉴定出一种新的致命疾病实体,发展到揭示其遗传病因,从而能够早期发现携带该基因的个体,并采取有效的预防早逝策略。