Erickson Brandon J, Mascarenhas Randy, Sayegh Eli T, Saltzman Bryan, Verma Nikhil N, Bush-Joseph Charles A, Cole Brian J, Bach Bernard R
Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, Illinois, U.S.A..
Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, Illinois, U.S.A.
Arthroscopy. 2015 Jun;31(6):1207-15. doi: 10.1016/j.arthro.2014.11.040. Epub 2015 Jan 28.
To conduct a systematic review of meta-analyses comparing nonoperative and operative treatment of patellar dislocations to elucidate the cause of the variation and to determine which meta-analysis provides the current best available evidence.
A systematic review of the literature to identify meta-analyses was performed. Data were extracted for patient outcomes and recurrent dislocations. Meta-analysis quality was assessed using the Oxman-Guyatt and Quality of Reporting of Meta-analyses systems. The Jadad algorithm was then applied to determine which meta-analysis provided the highest level of evidence.
Four meta-analyses met the eligibility criteria: 1 Level I evidence, 2 Level II evidence, and 1 Level III evidence. A total of 1,984 patients were included (997 underwent surgery whereas 987 underwent conservative treatment). Three meta-analyses found a lower subsequent patellar dislocation rate in patients managed operatively compared with nonoperatively, whereas one did not find a difference in recurrent dislocation rates between the operative and nonoperative groups. When the results of all the studies were combined, the overall redislocation rate was 29.4% and the rate of recurrent instability episodes was 32.8%. Patients treated operatively had a 24.0% rate of repeat patellar dislocation and a 32.7% rate of recurrent patellar instability, whereas patients treated nonoperatively had a 34.6% rate of repeat patellar dislocation and a 33.0% rate of recurrent instability. In addition, 1 meta-analysis found a significantly higher rate of patellofemoral osteoarthritis in the operative group. No differences in functional outcomes scores were seen between treatments. Two meta-analyses had low Oxman-Guyatt scores (<4), indicative of major flaws.
According to the best available evidence, operative treatment of acute patellar dislocations may result in a lower rate of recurrent dislocations than nonoperative treatment but does not improve functional outcome scores.
Level III, systematic review of Level I, II, and II studies.
对比较髌骨脱位非手术治疗与手术治疗的荟萃分析进行系统评价,以阐明差异的原因,并确定哪项荟萃分析提供了当前最佳的可用证据。
对文献进行系统检索以识别荟萃分析。提取患者结局和复发性脱位的数据。使用奥克斯曼 - 盖亚特和荟萃分析报告质量系统评估荟萃分析的质量。然后应用 Jadad 算法确定哪项荟萃分析提供了最高级别的证据。
四项荟萃分析符合纳入标准:1项I级证据、2项II级证据和1项III级证据。共纳入1984例患者(997例接受手术,987例接受保守治疗)。三项荟萃分析发现,与非手术治疗的患者相比,手术治疗的患者随后的髌骨脱位率较低,而一项荟萃分析未发现手术组与非手术组之间的复发性脱位率存在差异。当合并所有研究的结果时,总体再脱位率为29.4%,复发性不稳定发作率为32.8%。接受手术治疗的患者再次髌骨脱位率为24.0%,复发性髌骨不稳定率为32.7%,而接受非手术治疗的患者再次髌骨脱位率为34.6%,复发性不稳定率为33.0%。此外,1项荟萃分析发现手术组髌股关节炎的发生率显著更高。治疗之间在功能结局评分方面未见差异。两项荟萃分析的奥克斯曼 - 盖亚特评分较低(<4),表明存在重大缺陷。
根据现有最佳证据,急性髌骨脱位的手术治疗可能比非手术治疗导致更低的复发性脱位率,但并不能改善功能结局评分。
III级,对I、II和III级研究的系统评价。