Say Ferhat, Gürler Deniz, İnkaya Erkan, Bülbül Murat
Department of Orthopedics and Traumatology, Faculty of Medicine, Ondokuz Mayıs University, Samsun, Turkey.
Department of Orthopedics and Traumatology, Samsun Training and Research Hospital, Samsun, Turkey.
Acta Orthop Traumatol Turc. 2014;48(6):667-72. doi: 10.3944/AOTT.2014.13.0142.
The aim of this study was to compare the effects of platelet-rich plasma (PRP) and steroid injections in patients diagnosed with plantar fasciitis.
A total of 50 patients with chronic plantar fasciitis were included in the study and divided into 2 groups. In the PRP group (n=25), PRP taken from the patients' blood was activated using calcium chloride and injected in a single dose. In the steroid group (n=25), a single dose methylprednisolone with local anesthetic injection was given. Clinical evaluation was made using the American Foot and Ankle Score (AFAS) and the visual analog scale (VAS).
No complications were seen in any patients. Mean AFAS was 85.5 ± 4.2 at 6 weeks and 90.6 ± 2.6 at 6 months in the PRP group and 75.3 ± 4.8 and 80.3 ± 4.7, respectively, in the steroid group (p<0.001). The difference in the mean VAS between the PRP group (2.4 ± 0.8 and 1 ± 0.8) and the steroid group (4 ± 1.1 and 2.6 ± 0.9) at the 6th week and 6th month was statistically significant (p<0.001). Changes in AFAS and VAS scores were significantly higher in the PRP group (p<0.001).
The application of PRP appears to be more effective than steroid injection in terms of pain and functional results in the treatment of chronic plantar fasciitis.
本研究旨在比较富血小板血浆（PRP）和类固醇注射对诊断为足底筋膜炎患者的疗效。
本研究共纳入50例慢性足底筋膜炎患者，分为2组。PRP组（n = 25），将从患者血液中提取的PRP用氯化钙激活后单次注射。类固醇组（n = 25），给予单次剂量的甲基泼尼松龙加局部麻醉剂注射。采用美国足踝评分（AFAS）和视觉模拟量表（VAS）进行临床评估。
所有患者均未出现并发症。PRP组6周时平均AFAS为85.5±4.2，6个月时为90.6±2.6；类固醇组6周时平均AFAS为75.3±4.8，6个月时为80.3±4.7（p<0.001）。PRP组（2.4±0.8和1±0.8）与类固醇组（4±1.1和2.6±0.9）在第6周和第6个月时平均VAS的差异具有统计学意义（p<0.001）。PRP组AFAS和VAS评分的变化显著更高（p<0.001）。
在慢性足底筋膜炎的治疗中，就疼痛和功能结果而言，PRP的应用似乎比类固醇注射更有效。
