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富血小板血浆与皮质类固醇注射治疗慢性足底筋膜炎的比较:一项随机对照试验。

Comparison of Platelet-Rich Plasma and Corticosteroid Injections for Chronic Plantar Fasciitis: A Randomized Controlled Trial.

作者信息

Kumar Krishan, Rao Vikas, Panda Amrit, K G Sathyendra, Buddhist Harshvardhan

机构信息

Orthopaedics, Sports Injury Centre, Vardhman Mahavir Medical College (VMMC) & Safdarjung Hospital, New Delhi, IND.

Orthopaedics, Employees State Insurance-Post Graduate Institute of Medical Sciences and Research (ESI-PGIMSR), New Delhi, IND.

出版信息

Cureus. 2024 May 4;16(5):e59656. doi: 10.7759/cureus.59656. eCollection 2024 May.

Abstract

BACKGROUND

Plantar fasciitis is a common and debilitating foot condition, with varying treatment options and inconsistent outcomes. The objective of this study was to assess and compare the effectiveness of autologous platelet-rich plasma (PRP) injections and corticosteroid injections in treating persistent plantar fasciitis.

METHODS

In this study, a total of 70 patients suffering from chronic plantar fasciitis were randomly divided into two groups, i.e., one receiving PRP injections (n=35) and the other receiving corticosteroid injections (n=35). The visual analog scale (VAS) was used to assess pain outcomes, while the American Orthopaedic Foot and Ankle Society (AOFAS) score was used to assess functional status. Patients were assessed before the injection and then followed up at 15 days, one month, three months, and six months after the injection.

RESULTS

The baseline VAS and AOFAS scores were similar between the two groups. However, the PRP group showed significantly greater improvements in VAS and AOFAS scores compared to the corticosteroid group at the one-month, three-month, and six-month follow-ups (p<0.05). The PRP group had a higher proportion of patients with mild or moderate pain and better functional outcomes at later time points.

CONCLUSIONS

Autologous PRP injections are superior to corticosteroid injections in terms of long-term pain alleviation and functional improvement for patients suffering from chronic plantar fasciitis. Platelet-rich plasma should be regarded as a feasible therapeutic choice for this condition, especially in individuals who have not shown improvement with conservative treatment.

摘要

背景

足底筋膜炎是一种常见且使人衰弱的足部疾病,治疗方法多样,疗效不一。本研究的目的是评估和比较自体富血小板血浆(PRP)注射和皮质类固醇注射治疗持续性足底筋膜炎的有效性。

方法

在本研究中,共有70例慢性足底筋膜炎患者被随机分为两组,一组接受PRP注射(n = 35),另一组接受皮质类固醇注射(n = 35)。采用视觉模拟量表(VAS)评估疼痛结果,同时采用美国矫形足踝协会(AOFAS)评分评估功能状态。在注射前对患者进行评估,然后在注射后15天、1个月、3个月和6个月进行随访。

结果

两组的基线VAS和AOFAS评分相似。然而,在1个月、3个月和6个月的随访中,PRP组的VAS和AOFAS评分改善程度明显高于皮质类固醇组(p<0.05)。PRP组在后期有更高比例的轻度或中度疼痛患者,功能结果更好。

结论

对于慢性足底筋膜炎患者,自体PRP注射在长期缓解疼痛和改善功能方面优于皮质类固醇注射。富血小板血浆应被视为这种疾病的一种可行治疗选择,特别是对于那些保守治疗未显改善的个体。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4030/11147740/5981fbb95f8a/cureus-0016-00000059656-i01.jpg

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