Lal Ann K, Hibbard Judith U
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Illinois, 820 S Wood St, Chicago, IL, 60612, USA,
Arch Gynecol Obstet. 2015 Aug;292(2):299-305. doi: 10.1007/s00404-015-3628-y. Epub 2015 Feb 1.
The objective of the study is to characterize the maternal and neonatal morbidities of women with placenta previa.
This retrospective group study used the Consortium on Safe Labor electronic database, including 12 clinical centers, and 19 hospitals. Patients with placenta previa noted at the time of delivery were included. Maternal and neonatal variables were compared to a control group of women undergoing cesarean delivery with no previa. Logistic regression and general linear regression were used for the analysis, with p < 0.05 significance.
There were 19,069 patients in the study: 452 in the placenta previa group and 18,617 in the control group. Neonates born to mothers with placenta previa had lower gestational ages and birth weights. In univariate analysis only, these neonates were at increased risk of lower 5 min Apgar scores, neonatal intensive care unit admission, anemia, respiratory distress syndrome, mechanical ventilation, and intraventricular hemorrhage. There was no association of placenta previa with small for gestational age infants, congenital anomalies or death. As previously shown, women with placenta previa have significantly more maternal morbidities.
Increased maternal morbidity was noted; however, only those neonatal morbidities associated with preterm delivery occurred in the placenta previa group.
本研究的目的是描述前置胎盘孕妇的母体和新生儿发病情况。
这项回顾性群组研究使用了安全分娩联盟电子数据库，该数据库包括12个临床中心和19家医院。纳入分娩时诊断为前置胎盘的患者。将母体和新生儿变量与未患前置胎盘的剖宫产对照组女性进行比较。采用逻辑回归和一般线性回归进行分析，显著性水平为p < 0.05。
本研究共有19,069例患者：前置胎盘组452例，对照组18,617例。前置胎盘母亲所生新生儿的孕周和出生体重较低。仅在单因素分析中，这些新生儿5分钟阿氏评分较低、入住新生儿重症监护病房、贫血、呼吸窘迫综合征、机械通气和脑室内出血的风险增加。前置胎盘与小于胎龄儿、先天性畸形或死亡无关。如先前所示，前置胎盘女性的母体发病情况明显更多。
注意到母体发病率增加；然而，前置胎盘组仅出现与早产相关的那些新生儿发病情况。
