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在临床高危精神病状态下寻求帮助的青少年所报告的情绪和行为症状学。

Emotional and behavioral symptomatology reported by help-seeking youth at clinical high-risk for psychosis.

作者信息

Thompson Elizabeth, Kline Emily, Ellman Lauren M, Mittal Vijay, Reeves Gloria M, Schiffman Jason

机构信息

Department of Psychology, University of Maryland, Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250, United States.

Department of Psychology, Temple University, 1701 North 13th Street, Philadelphia, PA 19122, United States.

出版信息

Schizophr Res. 2015 Mar;162(1-3):79-85. doi: 10.1016/j.schres.2015.01.023. Epub 2015 Jan 28.

Abstract

Subthreshold psychosis-like experiences are typically the focus of psychosis-risk screening as they are associated with a greater propensity for future illness. Potentially prodromal individuals identified as being at clinical high-risk (CHR), however, report a variety of distressing and impairing mental health symptoms in addition to subthreshold psychosis symptoms, indicating that this population is of clinical interest regardless of whether or not they develop psychosis. In the current study, 90 young people (12-21) seeking mental health services completed the Behavior Assessment System for Children, Second Edition (BASC-2), a broad-range checklist of emotional and behavioral concerns and adaptive skills, followed by the Structured Interview for Psychosis-risk Syndromes to assess psychosis risk. Those who met criteria for CHR (n=35) reported elevated scores across several BASC-2 scales including depression, attention problems, locus of control, and sense of inadequacy compared to help-seeking youth without CHR (n=55). Most of these scales were also elevated compared to general population norms. Further, the CHR group had significantly lower scores on two adaptive scales, self-reliance and relations with parents, indicating more impairment in these domains. Results indicate that young people at CHR experience more pervasive and/or more severe symptomatology across several domains of clinical significance compared to a similar group of help-seeking youth not at CHR. Results from this study aid in the understanding of symptom correlates of CHR status beyond attenuated symptoms that can provide clinical information relevant for treatment.

摘要

阈下精神病性体验通常是精神病风险筛查的重点,因为它们与未来患病的更高倾向相关。然而,被确定为临床高危(CHR)的潜在前驱个体,除了阈下精神病症状外,还报告了各种令人痛苦和损害心理健康的症状,这表明无论他们是否发展为精神病,这一人群都具有临床研究价值。在当前研究中,90名寻求心理健康服务的年轻人(12 - 21岁)完成了儿童行为评估系统第二版(BASC - 2),这是一份关于情绪和行为问题以及适应技能的广泛清单,随后进行了精神病风险综合征结构化访谈以评估精神病风险。与未患CHR的求助青年(n = 55)相比,符合CHR标准的那些人(n = 35)在BASC - 2的几个量表上得分升高,包括抑郁、注意力问题、控制点和自卑感。与一般人群标准相比,这些量表中的大多数得分也有所升高。此外,CHR组在两个适应量表(自力更生和与父母的关系)上的得分显著更低,表明在这些领域存在更多损害。结果表明,与一组类似的未患CHR的求助青年相比,患CHR的年轻人在几个具有临床意义的领域经历了更普遍和/或更严重的症状。这项研究的结果有助于理解CHR状态的症状相关性,而不仅仅是可提供与治疗相关临床信息的减弱症状。

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