Lacour Brigitte, Clavel Jacqueline
Rev Prat. 2014 Nov;64(9):1264-9.
In France, cancer hits around 1700 children (0-14 years) each year. The age-standardized incidence rate for all cancers combined is 152 cases per million children per year, with a sex ratio of 1.2. In other terms, one child out of 440 develops a cancer before the age of 15 in industrial countries. The most frequent cancers were leukaemia (29%), embryonal tumours apart central nervous system (25%), central nervous system tumour (23%) and lymphoma (12%). The incidence varies between countries with higher overall rates in industrialized countries. These variations may reflect differences in diagnostic techniques or registration or in the distribution of possible risk factors. Five-year survival after childhood cancer has dramatically improved in the last 30 years, reaching yet 80%.
在法国，每年约有1700名儿童（0至14岁）罹患癌症。所有癌症综合的年龄标准化发病率为每年每百万儿童152例，男女比例为1.2。换言之，在工业化国家，每440名儿童中就有1名在15岁前患癌症。最常见的癌症是白血病（29%）、中枢神经系统以外的胚胎性肿瘤（25%）、中枢神经系统肿瘤（23%）和淋巴瘤（12%）。各国发病率有所不同，工业化国家总体发病率较高。这些差异可能反映出诊断技术、登记情况或潜在风险因素分布方面的差异。在过去30年里，儿童癌症后的五年生存率显著提高，目前已达到80%。
