Al-Asadi Jasim N, Ibrahim Sarah J
Department of Family and Community Medicine, College of Medicine, Basrah University, Basrah, Iraq. Email:
Asian Pac J Cancer Prev. 2018 Aug 24;19(8):2337-2341. doi: 10.22034/APJCP.2018.19.8.2337.
Background: Worldwide, childhood cancer is rare. In addition, a distinct variation in both incidence and type distribution was reported between countries. Aim: To estimate the incidence and mortality rates of childhood cancer in Basrah, Iraq during 2012-2016. Methods: This registry based descriptive study included children aged 0-14 years with primary cancer who were newly diagnosed in Basrah during 2012-2016. The types of malignant tumors were classified according to International Classification of Childhood Cancer, Version 3 (ICCC-3). The overall and specific incidence and mortality rates by age and sex were calculated per 100,000 population. Results: A total of 723 new cases of childhood cancer were registered during the five- year study period, with a male to-female ratio of 1.2/1. Children aged <4 years accounted for 43.1% of patients. The overall incidence rate was 13.74/100,000, and the age standardized incidence rate (ASIR) was 13.87/100,000. Boys showed higher incidence rate than girls (14.78 vs. 12.66/100,000). Leukemia was the most common type of childhood cancer accounting for 35.4%, followed by lymphoma (17.8%), and central nervous system tumors 11.9%. The overall cancer-specific mortality rate was 6.04/100,000 and the ASMR was 6.08/100,000 children. Conclusion: The incidence rate of childhood cancer in Basrah as well as the cancer type distribution was comparable to that reported for developing countries.
在全球范围内，儿童癌症较为罕见。此外，各国之间在发病率和类型分布上存在明显差异。目的：估计2012 - 2016年伊拉克巴士拉儿童癌症的发病率和死亡率。方法：这项基于登记处的描述性研究纳入了2012 - 2016年在巴士拉新诊断出原发性癌症的0 - 14岁儿童。恶性肿瘤类型根据《国际儿童癌症分类第3版》（ICCC - 3）进行分类。按年龄和性别计算每10万人口的总体及特定发病率和死亡率。结果：在为期五年的研究期间，共登记了723例儿童癌症新病例，男女比例为1.2∶1。年龄＜4岁的儿童占患者的43.1%。总体发病率为13.74/10万，年龄标准化发病率（ASIR）为13.87/10万。男孩的发病率高于女孩（分别为14.78/10万和12.66/10万）。白血病是最常见的儿童癌症类型，占35.4%，其次是淋巴瘤（17.8%）和中枢神经系统肿瘤（11.9%）。总体癌症特异性死亡率为6.04/10万，儿童年龄标准化死亡率（ASMR）为6.08/10万。结论：巴士拉儿童癌症的发病率以及癌症类型分布与发展中国家报告的情况相当。
