Ho L T, Chern Y F, Lin M T
Department of Internal Medicine, Veterans General Hospital, Taipei, Taiwan.
Experientia. 1989 Feb 15;45(2):161-2. doi: 10.1007/BF01954859.
The level of somatostatin in the hypothalamus was higher in satiated rats than in hungry rats. Elevating hypothalamic somatostatin levels by administering somatostatin into the hypothalamus produced a decrease in food intake, whereas lowering hypothalamic somatostatin levels by administering cysteamine into the peritoneal cavity produced an increase in food intake in rats.