Liu Xiaohua, Landon Mark B, Cheng Weiwei, Chen Yan
Department of Obstetrics, International Peace Maternity and Child Health Hospital, Shanghai Jiaotong University. Shanghai, China.
Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, The Ohio State University College of Medicine, Columbus, OH.
Am J Obstet Gynecol. 2015 Jun;212(6):817.e1-9. doi: 10.1016/j.ajog.2015.01.043. Epub 2015 Jan 29.
The purpose of this study was to describe the risks and benefits of cesarean delivery on maternal request (CDMR) in a Chinese population.
A retrospective cohort study of mode of delivery was conducted at the largest obstetric center in Shanghai, China, from 2007-2013. Eligibility criteria included singleton term nulliparous women with vertex presentation; women with major fetal anomalies or stillbirth before labor were excluded.
A total of 66,226 women were included in the analysis: 40,560 women (61.2%) had planned vaginal birth, with 32,833 spontaneous vaginal deliveries (80.9%), 4990 intrapartum CDs (12.3%), and 2737 assisted vaginal deliveries (6.7%). A total of 16,333 women (24.7%) underwent CDMR. We observed no significant difference between the CDMR and planned vaginal delivery groups in the frequencies of maternal intensive care unit admission (0.2% vs 0.2%), severe postpartum hemorrhage (0.5% vs 0.5%), maternal infection (1.3% vs 1.3%), organ injuries (0.4‰ vs 0.5‰), and thromboembolic disorders (0.1‰ vs 0.1‰). The perinatal mortality rate was similar in the 2 groups (0.4‰ vs 0.6‰; adjusted odds ratio, 0.51; 95% confidence interval, 0.20-1.30; P = .159). The frequencies of birth trauma (0.2‰ vs 1.1‰), neonatal infection (0.4% vs 0.7%), hypoxic ischemic encephalopathy (0.4‰ vs 1.8‰), and meconium aspiration syndrome (0.2‰ vs 0.6‰) were lower; the frequency of respiratory-distress syndrome (0.6% vs 0.4%) was higher in the CDMR group.
Compared with nulliparous women who tried vaginal delivery, women who underwent CDMR had similar short-term maternal outcomes with some neonatal benefit.
本研究旨在描述在中国人群中,应产妇要求剖宫产(CDMR)的风险和益处。
对2007年至2013年期间在中国上海最大的产科中心进行的分娩方式进行回顾性队列研究。纳入标准包括单胎足月初产妇且为头先露;排除临产前有严重胎儿畸形或死产的妇女。
共有66226名妇女纳入分析:40560名妇女(61.2%)计划经阴道分娩,其中32833例自然阴道分娩(80.9%),4990例产时剖宫产(12.3%),2737例阴道助产(6.7%)。共有16333名妇女(24.7%)接受了CDMR。我们观察到,在产妇重症监护病房入住率(0.2%对0.2%)、严重产后出血(0.5%对0.5%)、产妇感染(1.3%对1.3%)、器官损伤(0.4‰对0.5‰)和血栓栓塞性疾病(0.1‰对0.1‰)的发生率方面,CDMR组和计划经阴道分娩组之间无显著差异。两组围产期死亡率相似(0.4‰对0.6‰;校正比值比,0.51;95%置信区间,0.20 - 1.30;P = 0.159)。CDMR组的出生创伤(0.2‰对1.1‰)、新生儿感染(0.4%对0.7%)、缺氧缺血性脑病(0.4‰对1.8‰)和胎粪吸入综合征(0.2‰对0.6‰)的发生率较低;呼吸窘迫综合征的发生率较高(0.6%对0.4%)。
与尝试经阴道分娩的初产妇相比,接受CDMR的妇女短期产妇结局相似,对新生儿有一些益处。