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与未临产剖宫产相比,足月引产相关的孕产妇及新生儿发病率。

Maternal and neonatal morbidities associated with cesarean delivery without labor compared with induction of labor around term.

作者信息

Moon Hanna, Lee Ji Hyun, Kim Eui Hyeok

机构信息

Department of Obstetrics and Gynecology, Yonsei University, Seoul, Korea.

National Health Insurance Service Ilsan Hospital, Goyang, Korea.

出版信息

Obstet Gynecol Sci. 2022 Jan;66(1):11-19. doi: 10.5468/ogs.22248. Epub 2022 Dec 19.

Abstract

OBJECTIVE

We aimed to compare the maternal and neonatal morbidities associated with elective cesarean delivery (CD) without labor and those associated with induction of labor (IOL) at ≥38 weeks of gestation.

METHODS

This retrospective observational study from 2013 to 2020 included singleton pregnancies in nulliparous women at ≥38 weeks of gestation. Maternal and neonatal morbidities associated with elective CD without labor were compared with those associated with IOL.

RESULTS

Altogether, 395 women were recruited. Among these, 326 underwent delivery through IOL, while 69 underwent elective CD. The elective CD group exhibited higher maternal age, lower gestational age at birth, and lower neonatal birth weight than the IOL group (P<0.001). Moreover, the elective CD group exhibited longer hospital stay, higher rate of uterotonic agent usage, and lower rate of antibiotic usage after discharge. However, no differences were observed in postpartum bleeding, readmission, or number of outpatient visits (>3) after discharge between the groups. Perinatal morbidities were similar between the groups except the incidence of meconium-stained amniotic fluid. Elective CD exhibited similar rates of complications related to composite maternal morbidity when compared with IOL, but had a lower risk of complications related to composite neonatal morbidity (relative risk, 0.45; 95% confidence interval, 0.24-0.85).

CONCLUSION

Elective CD and IOL had similar rates of composite maternal morbidity but the former exhibited some benefits against obstetric wound infection. The elective CD group exhibited a decreased risk of composite neonatal morbidity despite lower gestational age at birth and higher maternal age.

摘要

目的

我们旨在比较妊娠≥38周时计划性剖宫产(CD)未临产与引产(IOL)相关的孕产妇及新生儿发病率。

方法

这项2013年至2020年的回顾性观察性研究纳入了妊娠≥38周的初产妇单胎妊娠。比较了计划性剖宫产未临产与引产相关的孕产妇及新生儿发病率。

结果

共招募了395名女性。其中,326例通过引产分娩,69例接受了计划性剖宫产。计划性剖宫产组产妇年龄较大,出生时孕周较小,新生儿出生体重较低,均低于引产组(P<0.001)。此外,计划性剖宫产组住院时间更长,宫缩剂使用率更高,出院后抗生素使用率更低。然而,两组之间在产后出血、再次入院或出院后门诊就诊次数(>3次)方面未观察到差异。除羊水粪染发生率外,两组围产期发病率相似。与引产相比,计划性剖宫产在复合孕产妇发病率相关并发症发生率方面相似,但复合新生儿发病率相关并发症风险较低(相对风险,0.45;95%置信区间,0.24-0.85)。

结论

计划性剖宫产和引产的复合孕产妇发病率相似,但前者在预防产科伤口感染方面有一些益处。尽管计划性剖宫产组出生时孕周较小且产妇年龄较大,但其复合新生儿发病率风险降低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb51/9877469/eb8f476f0224/ogs-22248f1.jpg

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