Ilic Milena, Ilic Irena
Department of Epidemiology, Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia E-mail :
Asian Pac J Cancer Prev. 2015;16(1):157-62. doi: 10.7314/apjcp.2015.16.1.157.
This descriptive epidemiological study aimed to analyse the mortality trends from gynaecological cancer in Serbia. Average annual percentage of change (AAPC) and the corresponding 95% confidence intervals (CIs) were computed for trend using joinpoint regression analysis. Nearly 25,000 gynaecological cancer deaths occurred in Serbia during the 1991-2010 period, with the average annual age-standardised mortality rate being 17.2 per 100,000 women. Increase of mortality was observed for cancer of the vulva and vagina (AAPC=+1.3%, 95% CI=0.1 to 2.6), ovarian cancer (AAPC=+0.8%, 95% CI=0.4-1.3) and for cervical cancer (AAPC=+0.7%, 95% CI=0.3 to 1.1). Mortality rates for gynaecological cancer overall declined in women aged 30-39 years, but mortality was increased in middle-aged women (for cervical cancer) and in the elderly (for ovarian cancer). Improvements to and implementation of the national cervical cancer screening programme conducted in 2013 and expected to be finalised in the following years throughout Serbia should contribute to improvement.
这项描述性流行病学研究旨在分析塞尔维亚妇科癌症的死亡率趋势。使用连接点回归分析计算趋势的平均年度变化百分比(AAPC)及其相应的95%置信区间(CI)。1991年至2010年期间,塞尔维亚发生了近25000例妇科癌症死亡病例,年龄标准化死亡率平均为每10万名女性17.2例。观察到外阴和阴道癌(AAPC=+1.3%,95%CI=0.1至2.6)、卵巢癌(AAPC=+0.8%,95%CI=0.4-1.3)和宫颈癌(AAPC=+0.7%,95%CI=0.3至1.1)的死亡率有所上升。30-39岁女性的妇科癌症总体死亡率有所下降,但中年女性(宫颈癌)和老年女性(卵巢癌)的死亡率有所上升。2013年在塞尔维亚开展并预计在接下来几年完成的全国宫颈癌筛查计划的改进和实施应有助于改善情况。