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联合颅外-颅内搭桥手术与支架辅助弹簧圈栓塞治疗伴有破裂宽颈基底动脉主干动脉瘤的烟雾病:一例报告

Combined extracranial-intracranial bypass surgery with stent-assisted coil embolization for moyamoya disease with a ruptured wide-necked basilar trunk aneurysm: a case report.

作者信息

Jiang Hanqiang, Ni Wei, Lei Yu, Li Yanjiang, Gu Yuxiang

机构信息

Fudan University, Huashan Hospital, Department of Neurosurgery, Shanghai, China.

出版信息

Turk Neurosurg. 2015;25(1):180-5. doi: 10.5137/1019-5149.JTN.10043-13.0.

Abstract

A ruptured wide-necked basilar trunk aneurysm is uncommon in patients with moyamoya disease. The optimal treatment is unclear. We report a safe and beneficial treatment modality for moyamoya disease with aneurysms located in the posterior circulation. A 37-year-old man presenting with subarachnoid hemorrhage was admitted to our hospital. Emergent cerebral angiography demonstrated moyamoya disease associated with a wide-necked basilar trunk aneurysm. We performed bilateral extracranial-intracranial bypass surgeries prior to stent-assisted coil embolization of the aneurysm after the acute phase. No complication occurred and the patient was discharged with no neurological deficit. Follow-up digital subtraction angiography (DSA) performed 6 months after the surgery showed that all the anastomosises were patent and bilateral collateral vascular compensation was fully established with no recanalization of the basilar trunk aneurysm post embolization.We also found that high-flow bypass did not contribute to cerebral revascularization as imagined despite the good patency. Combined extracranial-intracranial bypass surgery with endovascular treatment proved to be an efficient therapeutic modality for moyamoya disease with aneurysms located in the posterior circulation. High-flow bypass surgery was not essential due to the inefficiency and the high risk of postoperative cerebral hyperperfusion syndrome.

摘要

破裂的宽颈基底动脉干动脉瘤在烟雾病患者中并不常见。最佳治疗方法尚不清楚。我们报告一种针对位于后循环的烟雾病合并动脉瘤的安全有效的治疗方式。一名37岁因蛛网膜下腔出血就诊的男性被收入我院。急诊脑血管造影显示烟雾病合并宽颈基底动脉干动脉瘤。急性期过后,我们在动脉瘤的支架辅助弹簧圈栓塞术前进行了双侧颅外-颅内搭桥手术。未发生并发症,患者出院时无神经功能缺损。术后6个月进行的随访数字减影血管造影(DSA)显示,所有吻合口通畅,双侧侧支血管代偿充分建立,栓塞术后基底动脉干动脉瘤未再通。我们还发现,尽管通畅性良好,但高流量搭桥并未如预期那样促进脑血运重建。颅外-颅内搭桥手术联合血管内治疗被证明是治疗位于后循环的烟雾病合并动脉瘤的有效治疗方式。由于效率低下和术后脑过度灌注综合征风险高,高流量搭桥手术并非必需。

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