哮喘患者中过敏与哮喘控制、生活质量及情绪状态之间的关系：一项横断面研究。
The relationship between allergy and asthma control, quality of life, and emotional status in patients with asthma: a cross-sectional study.
作者信息
Coban Hikmet, Aydemir Yusuf
机构信息
Department of Pulmonology, Sakarya University, Sakarya, Turkey.
Department of Pulmonology, Sakarya University, Sakarya, Turkey ; Training and Research Hospital, Sakarya University, 54100 Sakarya, Turkey.
出版信息
Allergy Asthma Clin Immunol. 2014 Dec 21;10(1):67. doi: 10.1186/s13223-014-0067-4. eCollection 2014.
BACKGROUND
Psychiatric comorbidities are prevalent in patients with chronic somatic disorders such as asthma. But, there is no clear evidence regarding the effect of atopic status and the type of sensitized allergen on emotional status. The aim of the present study was to investigate the effects of house dust mites and pollen allergies on emotional status, asthma control and the quality of life in patients with atopic asthma.
METHODS
The study included 174 consecutive patients who were diagnosed with asthma accoring to the GINA criteria and who did not receive therapy for their allergy. All patients underwent a skin prick test. The asthma control, quality of life, and emotional status were evaluated using the ACT (asthma control test), AQLQ (asthma-specific quality of life questionnaire), and HAD (hospital anxiety depression questionnaire).
RESULTS
Atopy was detected in 134 (78.7%) patients. Of those patients: 58 (33.3%) had anxiety and 83 (47.7%) had depression. There was no relationship between emotional status, atopic status, and the type of indoor/outdoor allergen. Furthermore, there was no relationship between atopy and asthma severity, asthma control, and the quality of life. The anxiety and depression scores were significantly higher and the quality of life scores lower in the uncontrolled asthma group. The ACT and AQLQ scores were also lower in the anxiety and depression groups.
CONCLUSIONS
It was concluded that anxiety and depression are prevalent in patients with uncontrolled asthma, and atopic status did not affect the scores in ACT, AQLQ, and emotional status tests.
背景
精神疾病共病在哮喘等慢性躯体疾病患者中很常见。但是，关于特应性状态和致敏变应原类型对情绪状态的影响，尚无明确证据。本研究的目的是调查屋尘螨和花粉过敏对特应性哮喘患者情绪状态、哮喘控制和生活质量的影响。
方法
该研究纳入了174例连续的患者，这些患者根据全球哮喘防治创议（GINA）标准被诊断为哮喘，且未接受过过敏治疗。所有患者均接受了皮肤点刺试验。使用哮喘控制测试（ACT）、哮喘特异性生活质量问卷（AQLQ）和医院焦虑抑郁量表（HAD）对哮喘控制、生活质量和情绪状态进行评估。
结果
134例（78.7%）患者检测出特应性。在这些患者中：58例（33.3%）有焦虑，83例（47.7%）有抑郁。情绪状态、特应性状态与室内/室外变应原类型之间无关联。此外，特应性与哮喘严重程度、哮喘控制及生活质量之间也无关联。未控制的哮喘组焦虑和抑郁评分显著更高，生活质量评分更低。焦虑和抑郁组的ACT和AQLQ评分也更低。
结论
得出的结论是，未控制的哮喘患者中焦虑和抑郁很常见，特应性状态并未影响ACT、AQLQ及情绪状态测试中的评分。
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