Haas Charles N
Departmetn of Civil, Architectural and Environmental Engineering, Drexel University, Philadelphia, Pennsylvania, USA.
PLoS Curr. 2014 Oct 14;6:ecurrents.outbreaks.2ab4b76ba7263ff0f084766e43abbd89. doi: 10.1371/currents.outbreaks.2ab4b76ba7263ff0f084766e43abbd89.
21 days has been regarded as the appropriate quarantine period for holding individuals potentially exposed to Ebola Virus (EV) to reduce risk of contagion. There does not appear to be a systematic discussion of the basis for this period.
The prior estimates for incubation time to EV were examined, along with data on the first 9 months of the current outbreak. These provided estimates of the distribution of incubation times.
A 21 day period for quarantine may result in the release of individuals with a 0.2 - 12% risk of release prior to full opportunity for the incubation to proceed. It is suggested that a detailed cost-benefit assessment, including considering full transmission risks, needs to occur in order to determine the appropriate quarantine period for potentially exposed individuals.
21天被视为对可能接触埃博拉病毒(EV)的个人进行隔离的适宜期限,以降低传染风险。对于这一期限的依据,似乎尚无系统性讨论。
研究了此前对埃博拉病毒潜伏期的估计,以及当前疫情最初9个月的数据。这些数据提供了潜伏期分布的估计。
21天的隔离期可能导致在潜伏期充分发展之前就放走有0.2%至12%释放风险的个体。建议进行详细的成本效益评估,包括考虑全面的传播风险,以便确定对可能接触者的适宜隔离期。