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小儿神经囊尾蚴病:荷兰报告的3例临床表现各异的病例

Pediatric neurocysticercosis: three cases presented in the Netherlands with divergent clinical presentations.

作者信息

van de Pol Laura A, van Doeveren T E M, van der Kuip M, Wolf N I, Vermeulen R J

机构信息

Department of Child Neurology, VU University Medical Center, Amsterdam, The Netherlands.

Department of Pediatric Infectious Diseases and Immunology, VU University Medical Center, Amsterdam, The Netherlands.

出版信息

Neuropediatrics. 2015 Apr;46(2):130-3. doi: 10.1055/s-0034-1399753. Epub 2015 Feb 2.

DOI:10.1055/s-0034-1399753
PMID:25642807
Abstract

BACKGROUND

Neurocysticercosis is a helminthic disease that affects the central nervous system by the larvae of the Taenia solium, the pork tapeworm. Because of the growing number of immigrants from endemic areas, its incidence is increasing in Western Europe.

CASES

We describe three children, aged between 2 and 13 years, two of whom have a definite and one a probable diagnosis of neurocysticercosis based on the "Del Brutto criteria." They presented with different symptoms and signs: symptomatic epilepsy, asymmetric cerebral palsy, and headache. Serological evaluation was negative in two of the three cases. All cases showed comparable abnormalities on magnetic resonance imaging of the brain: solitary or multiple, cystic lesions, with surrounding edema. In one of them, the "scolex" (part of the larvae) could be visualized. One case was treated with albendazole, the other two cases did not receive medication.

CONCLUSION

A prompt diagnosis of neurocysticercosis by recognition of its typical brain lesions is important to prevent unnecessary diagnostic tests and treatment.

摘要

背景

神经囊尾蚴病是一种由猪带绦虫幼虫感染中枢神经系统引起的蠕虫病。由于来自流行地区的移民数量不断增加,其在西欧的发病率正在上升。

病例

我们描述了三名年龄在2至13岁之间的儿童,其中两名根据“德尔布鲁托标准”被确诊为神经囊尾蚴病,一名可能患有该病。他们表现出不同的症状和体征:症状性癫痫、不对称性脑瘫和头痛。三例中有两例血清学评估为阴性。所有病例在脑部磁共振成像上均显示出类似的异常:单个或多个囊性病变,伴有周围水肿。其中一例可看到“头节”(幼虫的一部分)。一例接受了阿苯达唑治疗,另外两例未接受药物治疗。

结论

通过识别典型的脑部病变及时诊断神经囊尾蚴病对于避免不必要的诊断检查和治疗非常重要。

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Pediatric neurocysticercosis: three cases presented in the Netherlands with divergent clinical presentations.小儿神经囊尾蚴病:荷兰报告的3例临床表现各异的病例
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