Greysen S Ryan, Stijacic Cenzer Irena, Auerbach Andrew D, Covinsky Kenneth E
Division of Hospital Medicine, University of California, San Francisco.
Division of Geriatric Medicine, University of California, San Francisco3San Francisco Veterans Affairs Medical Center, San Francisco, California.
JAMA Intern Med. 2015 Apr;175(4):559-65. doi: 10.1001/jamainternmed.2014.7756.
Medicare currently penalizes hospitals for high readmission rates for seniors but does not account for common age-related syndromes, such as functional impairment.
To assess the effects of functional impairment on Medicare hospital readmissions given the high prevalence of functional impairments in community-dwelling seniors.
DESIGN, SETTING, AND PARTICIPANTS: We created a nationally representative cohort of 7854 community-dwelling seniors in the Health and Retirement Study, with 22,289 Medicare hospitalizations from January 1, 2000, through December 31, 2010.
Outcome was 30-day readmission assessed by Medicare claims. The main predictor was functional impairment determined from the Health and Retirement Study interview preceding hospitalization, stratified into the following 5 levels: no functional impairments, difficulty with 1 or more instrumental activities of daily living, difficulty with 1 or more activities of daily living (ADL), dependency (need for help) in 1 to 2 ADLs, and dependency in 3 or more ADLs. Adjustment variables included age, race/ethnicity, sex, annual income, net worth, comorbid conditions (Elixhauser score from Medicare claims), and prior admission. We performed multivariable logistic regression to adjust for clustering at the patient level to characterize the association of functional impairments and readmission.
Patients had a mean (SD) age of 78.5 (7.7) years (range, 65-105 years); 58.4% were female, 84.9% were white, 89.6% reported 3 or more comorbidities, and 86.0% had 1 or more hospitalizations in the previous year. Overall, 48.3% had some level of functional impairment before admission, and 15.5% of hospitalizations were followed by readmission within 30 days. We found a progressive increase in the adjusted risk of readmission as the degree of functional impairment increased: 13.5% with no functional impairment, 14.3% with difficulty with 1 or more instrumental activities of daily living (odds ratio [OR], 1.06; 95% CI, 0.94-1.20), 14.4% with difficulty with 1 or more ADL (OR, 1.08; 95% CI, 0.96-1.21), 16.5% with dependency in 1 to 2 ADLs (OR, 1.26; 95% CI, 1.11-1.44), and 18.2% with dependency in 3 or more ADLs (OR, 1.42; 95% CI, 1.20-1.69). Subanalysis restricted to patients admitted with conditions targeted by Medicare (ie, heart failure, myocardial infarction, and pneumonia) revealed a parallel trend with larger effects for the most impaired (16.9% readmission rate for no impairment vs 25.7% for dependency in 3 or more ADLs [OR, 1.70; 95% CI, 1.04-2.78]).
Functional impairment is associated with increased risk of 30-day all-cause hospital readmission in Medicare seniors, especially those admitted for heart failure, myocardial infarction, or pneumonia. Functional impairment may be an important but underaddressed factor in preventing readmissions for Medicare seniors.
医疗保险目前会因老年人的高再入院率而对医院进行处罚,但并未考虑常见的与年龄相关的综合征,如功能障碍。
鉴于社区居住老年人中功能障碍的高患病率,评估功能障碍对医疗保险患者医院再入院的影响。
设计、设置和参与者:我们在健康与退休研究中创建了一个具有全国代表性的7854名社区居住老年人的队列,涵盖了2000年1月1日至2010年12月31日期间的22289次医疗保险住院病例。
结局为通过医疗保险理赔评估的30天再入院情况。主要预测因素是根据住院前健康与退休研究访谈确定的功能障碍,分为以下5个级别:无功能障碍、1项或多项日常生活工具性活动有困难、1项或多项日常生活活动(ADL)有困难、1至2项ADL需要依赖(他人帮助)以及3项或更多ADL需要依赖。调整变量包括年龄、种族/民族、性别、年收入、净资产、合并症(根据医疗保险理赔得出的埃利克斯豪泽评分)和既往住院情况。我们进行多变量逻辑回归以调整患者层面的聚类情况,从而描述功能障碍与再入院之间的关联。
患者的平均(标准差)年龄为78.5(7.7)岁(范围为65 - 105岁);58.4%为女性,84.9%为白人,89.6%报告有3种或更多合并症,86.0%在上一年有1次或更多次住院经历。总体而言,48.3%的患者在入院前存在某种程度的功能障碍,15.5%的住院患者在30天内再次入院。我们发现,随着功能障碍程度的增加,调整后的再入院风险呈逐步上升趋势:无功能障碍者为13.5%,1项或多项日常生活工具性活动有困难者为14.3%(比值比[OR]为1.06;95%置信区间为0.94 - 1.20),1项或多项ADL有困难者为14.4%(OR为1.08;95%置信区间为0.96 - 1.21),1至2项ADL需要依赖者为16.5%(OR为1.26;95%置信区间为1.11 - 1.44),3项或更多ADL需要依赖者为18.2%(OR为1.42;95%置信区间为1.20 - 1.69)。针对因医疗保险所关注疾病(即心力衰竭、心肌梗死和肺炎)入院的患者进行的亚分析显示出类似趋势,且功能障碍最严重者的影响更大(无功能障碍者的再入院率为16.9%,而3项或更多ADL需要依赖者为25.7%[OR为1.70;95%置信区间为1.04 - 2.78])。
功能障碍与医疗保险参保老年人30天全因医院再入院风险增加相关,尤其是因心力衰竭、心肌梗死或肺炎入院的患者。功能障碍可能是预防医疗保险参保老年人再入院的一个重要但未得到充分关注的因素。