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医院再入院减少计划与急性心肌梗死、心力衰竭和肺炎住院期间及出院后死亡率的关联。

Association of the Hospital Readmissions Reduction Program With Mortality During and After Hospitalization for Acute Myocardial Infarction, Heart Failure, and Pneumonia.

机构信息

Division of Cardiology, University of Texas Southwestern Medical Center, Dallas.

Clover Health, Jersey City, New Jersey.

出版信息

JAMA Netw Open. 2018 Sep 7;1(5):e182777. doi: 10.1001/jamanetworkopen.2018.2777.

Abstract

IMPORTANCE

The US Hospital Readmissions Reduction Program (HRRP) was associated with reduced readmissions among Medicare beneficiaries hospitalized for acute myocardial infarction (AMI), heart failure (HF), and pneumonia. It is important to assess whether there has been a signal for concomitant harm with an increase in mortality.

OBJECTIVE

To evaluate whether the announcement or the implementation of HRRP was associated with an increase in either in-hospital or 30-day postdischarge mortality following hospitalization for AMI, HF, or pneumonia.

DESIGN, SETTING, AND PARTICIPANTS: In this cohort study, using Medicare data, all hospitalizations for AMI, HF, and pneumonia were identified among fee-for-service Medicare beneficiaries aged 65 years and older from January 1, 2006, to December 31, 2014. These were assessed for changes in trends for risk-adjusted rates of in-hospital and 30-day postdischarge mortality after announcement and implementation of the HRRP using an interrupted time series framework. Analyses were done in November 2017 and December 2017.

EXPOSURES

Announcement of the HRRP in March 2010, and implementation of its penalties in October 2012.

MAIN OUTCOMES AND MEASURES

Monthly risk-adjusted rates of in-hospital and 30-day postdischarge mortality.

RESULTS

The sample included 1.7 million AMI, 4 million HF, and 3.5 million pneumonia hospitalizations. Between 2006 and 2014, in-hospital mortality decreased for the 3 conditions (AMI, from 10.4% to 9.7%; HF, from 4.3% to 3.5%; pneumonia, from 5.3% to 4.0%) while 30-day postdischarge mortality decreased from 7.4% to 7.0% for AMI (P for trend < .001), but increased from 7.4% to 9.2% for HF (P for trend < .001) and from 7.6% to 8.6% for pneumonia (P for trend < .001). Before the HRRP announcement, monthly postdischarge mortality was stable for AMI (slope for monthly change, 0.002%; 95% CI, -0.001% to 0.006% per month), and increased by 0.004% (95% CI, 0.000% to 0.007%) per month for HF and by 0.005% (95% CI, 0.002% to 0.008%) per month for pneumonia. There were no inflections in slope around HRRP announcement or implementation (P > .05 for all). In contrast, there were significant negative deflections in slopes for readmission rates at HRRP announcement for all conditions.

CONCLUSIONS AND RELEVANCE

Among Medicare beneficiaries, there was no evidence for an increase in in-hospital or postdischarge mortality associated with HRRP announcement or implementation-a period with substantial reductions in readmissions. The improvement in readmission was therefore not associated with any increase in in-hospital or 30-day postdischarge mortality.

摘要

重要性

美国医院再入院减少计划(HRRP)与医疗保险受益人因急性心肌梗死(AMI)、心力衰竭(HF)和肺炎住院的再入院减少有关。评估死亡率是否存在伴随伤害的信号增加是很重要的。

目的

评估 HRRP 的宣布或实施是否与 AMI、HF 或肺炎住院后院内或 30 天出院后死亡率的增加相关。

设计、地点和参与者:在这项队列研究中,使用医疗保险数据,从 2006 年 1 月 1 日至 2014 年 12 月 31 日,确定了所有 65 岁及以上的 Medicare 服务收费受益人中 AMI、HF 和肺炎的所有住院治疗情况。使用中断时间序列框架评估 HRRP 宣布和实施后,风险调整的院内和 30 天出院后死亡率的趋势变化。分析于 2017 年 11 月和 2017 年 12 月进行。

暴露

2010 年 3 月宣布 HRRP,2012 年 10 月实施其处罚措施。

主要结果和测量

每月风险调整的院内和 30 天出院后死亡率。

结果

样本包括 170 万例 AMI、400 万例 HF 和 350 万例肺炎住院治疗。在 2006 年至 2014 年期间,3 种情况下的院内死亡率均有所下降(AMI,从 10.4%降至 9.7%;HF,从 4.3%降至 3.5%;肺炎,从 5.3%降至 4.0%),而 30 天出院后死亡率从 AMI 的 7.4%降至 7.0%(趋势 P<.001),但 HF 从 7.4%升至 9.2%(趋势 P<.001),肺炎从 7.6%升至 8.6%(趋势 P<.001)。在 HRRP 宣布之前,AMI 的出院后每月死亡率保持稳定(每月变化的斜率为 0.002%;95%CI,每月 0.001%至 0.006%),HF 每月增加 0.004%(95%CI,0.000%至 0.007%),肺炎每月增加 0.005%(95%CI,0.002%至 0.008%)。HRRP 宣布或实施前后的斜率没有明显的拐点(所有 P>.05)。相比之下,所有条件下的 HRRP 宣布时的再入院率斜率都有明显的负向偏离。

结论和相关性

在医疗保险受益人中,没有证据表明 HRRP 宣布或实施与死亡率增加相关——这一时期的再入院率大幅下降。因此,再入院率的改善与院内或 30 天出院后死亡率的增加无关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e54/6324473/a1e4e78bb5df/jamanetwopen-1-e182777-g001.jpg

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