St. Joseph's Healthcare Hamilton, Room F-544, 50 Charlton Avenue East, Hamilton, ON L8N 4A6, Canada.
Nat Rev Cardiol. 2015 Mar;12(3):133-4. doi: 10.1038/nrcardio.2015.7. Epub 2015 Feb 3.
The perioperative management of patients with atrial fibrillation who require an elective surgical or other invasive procedure is an area of ongoing uncertainty. Accumulating evidence from observational studies suggests that the use of bridging anticoagulation with heparin, although well-intentioned, might not reduce perioperative thromboembolism and can increase bleeding.
择期手术或其他有创操作的房颤患者的围手术期管理仍然存在诸多不确定因素。越来越多的观察性研究证据表明,肝素桥接抗凝尽管初衷良好,但可能并不能降低围手术期血栓栓塞风险,反而可能增加出血风险。