Kimmoun Antoine, Levy Bruno
Crit Care. 2014 Dec 18;18(6):694. doi: 10.1186/s13054-014-0694-7.
Patients with distributive shock still have a high mortality rate and remain an important issue for intensivists. Management of catecholamine-resistant shock in these patients poses a challenging problem. Despite significant advances in the knowledge of its pathophysiology, all innovative therapeutic approaches and interventions have failed to improve outcome. In the previous issue of Critical Care, Chawla and colleagues explored the impact of angiotensin II administration in patients with persistent hypotension despite adapted hemodynamic resuscitation. The authors demonstrate that, in case of distributive shock, angiotensin II is an effective vasopressor therapy. Its impact on outcome and adverse effects still needs to be further explored.
分布性休克患者的死亡率仍然很高，仍然是重症监护医生面临的一个重要问题。对这些患者进行抗儿茶酚胺休克的管理是一个具有挑战性的问题。尽管在其病理生理学知识方面取得了重大进展，但所有创新的治疗方法和干预措施都未能改善预后。在上一期《重症监护》杂志中，Chawla及其同事探讨了在经过适当的血流动力学复苏后仍持续低血压的患者中使用血管紧张素II的影响。作者证明，在分布性休克的情况下，血管紧张素II是一种有效的血管升压治疗方法。其对预后和不良反应的影响仍需进一步探索。
