Brain Sciences Center, Minneapolis Veterans Affairs Health Care System, Minneapolis, MN 55417, USA; Department of Neuroscience, University of Minnesota, Minneapolis, MN 55455, USA; Department of Neurology, University of Minnesota, Minneapolis, MN 55455, USA.
Brain Sciences Center, Minneapolis Veterans Affairs Health Care System, Minneapolis, MN 55417, USA; Department of Neurology, University of Minnesota, Minneapolis, MN 55455, USA.
Curr Opin Neurobiol. 2015 Aug;33:34-9. doi: 10.1016/j.conb.2015.01.012. Epub 2015 Jan 31.
The issue of coding of movement in the motor cortex has recently acquired special significance due to its fundamental importance in neuroprosthetic applications. The challenge of controlling a prosthetic arm by processed motor cortical activity has opened a new era of research in applied medicine but has also provided an 'acid test' for hypotheses regarding coding of movement in the motor cortex. The successful decoding of movement information from the activity of motor cortical cells using their directional tuning and population coding has propelled successful neuroprosthetic applications and, at the same time, asserted the utility of those early discoveries, dating back to the early 1980s.
由于在神经假肢应用中的重要性，运动在运动皮层中的编码问题最近获得了特殊的意义。通过处理运动皮层活动来控制假肢手臂的挑战为应用医学的研究开辟了一个新时代，但也为运动皮层中运动编码的假设提供了一个“严峻考验”。使用运动皮层细胞的方向调谐和群体编码从活动中解码运动信息已推动了成功的神经假肢应用，同时也证实了那些可以追溯到 20 世纪 80 年代早期的早期发现的实用性。
