Zhang Sheng, Yu Xiaoqiang, Feng Xiujuan, Yamamoto Yoshinori, Bao Ming
State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 116023, China.
Chem Commun (Camb). 2015 Mar 4;51(18):3842-5. doi: 10.1039/c4cc10373d.
Palladium-catalyzed allylation reactions of 2-(chloromethyl)thiophenes, 2-(chloromethyl)furans, and N-protected 2-(chloromethyl)-1H-pyrroles with allyltributylstannane were described in this study. This type of allylation reaction regioselectively occurred on the heteroarene rings to produce allylated dearomatization products or allylated heteroarenes with satisfactory yields.
本研究描述了钯催化的2-（氯甲基）噻吩、2-（氯甲基）呋喃和N-保护的2-（氯甲基）-1H-吡咯与烯丙基三丁基锡的烯丙基化反应。这种烯丙基化反应区域选择性地发生在杂芳烃环上，以令人满意的产率生成烯丙基化脱芳构化产物或烯丙基化杂芳烃。
