Venhovens J, Meulstee J, Verhagen W I M
Department of Neurology and Clinical Neurophysiology, Canisius Wilhelmina Hospital, The Netherlands.
Department of Neurology and Clinical Neurophysiology, Canisius Wilhelmina Hospital, The Netherlands.
Clin Neurophysiol. 2016 Jan;127(1):40-49. doi: 10.1016/j.clinph.2014.12.021. Epub 2015 Jan 16.
Several types of acoustic stimulation (i.e. tone bursts or clicks), bone-conducted vibration, forehead taps, and galvanic stimulation elicit myogenic potentials. These can be recorded in cervical and ocular muscles, the so called vestibular evoked myogenic potentials (VEMPs). The cervical VEMP (cVEMP) resembles the vestibulo-collic reflex and the responses can be recorded from the ipsilateral sternocleidomastoid muscle. The ocular VEMP resembles the vestibulo-ocular reflex and can be recorded from extra-ocular muscles by a surface electrode beneath the contralateral infraorbital margin. Initially, the literature concerning VEMPs was limited to peripheral vestibular disorders, however, the field of VEMP testing is rapidly expanding, with an increasing focus on central neurological disorders. The current literature concerning VEMP abnormalities in central neurological disorders is critically reviewed, especially regarding the methodological aspects in relation to quality as well as the clinical interpretation of the VEMP results. Suggestions for further research are proposed as well as some clinically useful indications.
几种类型的听觉刺激（即短纯音或点击声）、骨传导振动、前额轻拍和电刺激可诱发肌源性电位。这些电位可在颈部和眼部肌肉中记录到，即所谓的前庭诱发肌源性电位（VEMP）。颈部VEMP（cVEMP）类似于前庭-颈反射，其反应可从同侧胸锁乳突肌记录到。眼部VEMP类似于前庭-眼反射，可通过对侧眶下缘下方的表面电极从眼外肌记录到。最初，关于VEMP的文献仅限于外周前庭疾病，然而，VEMP测试领域正在迅速扩展，越来越关注中枢神经系统疾病。本文对当前有关中枢神经系统疾病中VEMP异常的文献进行了批判性综述，尤其涉及与质量相关的方法学方面以及VEMP结果的临床解读。还提出了进一步研究的建议以及一些临床有用的指征。
