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旅行者的胃肠道症状

Gastrointestinal symptoms in travellers.

作者信息

McGregor Alastair C, Wright Stephen G

机构信息

Hospital for Tropical Diseases, London, UK, and Imported Fever Service, Rare and Imported Pathogens Laboratory, Public Health England, Porton Down, UK.

Hospital for Tropical Diseases, London, UK, and consultant physician, King Edward VII Hospital, London, UK

出版信息

Clin Med (Lond). 2015 Feb;15(1):93-5. doi: 10.7861/clinmedicine.15-1-93.

DOI:10.7861/clinmedicine.15-1-93
PMID:25650209
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4954536/
Abstract

Diarrhoea is probably the single most common medical complaint in returning travellers. The most common pathogens are entero-toxigenic Escherichia coli, Shigella, Salmonella and Campylobacter. Viruses, toxigenic Arcobacter and Bacteroides fragilis, as well as parasites such as Cryptosporidium sp, are increasingly recognised but are not tested for in most diagnostic laboratories. Blood in stools is a sign of invasive disease and should trigger exclusion of invasive amoebic disease. The use of empiric antibiotics may shorten illness but is complicated by the diversity of bacterial causes and emerging resistance.

摘要

腹泻可能是归国旅行者最常见的单一医学病症。最常见的病原体是产肠毒素大肠杆菌、志贺氏菌、沙门氏菌和弯曲杆菌。病毒、产毒素嗜水气单胞菌和脆弱拟杆菌,以及隐孢子虫等寄生虫越来越受到关注,但大多数诊断实验室并不对其进行检测。便血是侵袭性疾病的征兆,应排查侵袭性阿米巴病。经验性使用抗生素可能会缩短病程,但由于细菌病因的多样性和新出现的耐药性而变得复杂。

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本文引用的文献

1
Distinguishing tropical sprue from celiac disease in returning travellers with chronic diarrhoea: a diagnostic challenge?返回旅行者慢性腹泻时,如何区分热带口炎性腹泻与乳糜泻:诊断难题?
Travel Med Infect Dis. 2014 Jul-Aug;12(4):401-5. doi: 10.1016/j.tmaid.2014.05.001. Epub 2014 May 16.
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Geographic, symptomatic and laboratory predictors of parasitic and bacterial causes of diarrhoea in travellers.旅行者腹泻的寄生虫和细菌病因的地理、症状和实验室预测因素。
Trans R Soc Trop Med Hyg. 2012 Sep;106(9):549-53. doi: 10.1016/j.trstmh.2012.04.008. Epub 2012 Jul 20.
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Gastrointestinal infection as a trigger for inflammatory bowel disease.胃肠道感染作为炎症性肠病的诱因。
Curr Opin Gastroenterol. 2012 Jan;28(1):24-9. doi: 10.1097/MOG.0b013e32834c453e.
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Improved detection of five major gastrointestinal pathogens by use of a molecular screening approach.采用分子筛选方法提高五种主要胃肠道病原体的检测率。
J Clin Microbiol. 2010 Nov;48(11):4140-6. doi: 10.1128/JCM.01124-10. Epub 2010 Sep 22.
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Characterization of norovirus-associated traveler's diarrhea.诺如病毒相关性旅行者腹泻的特征。
Clin Infect Dis. 2010 Jul 15;51(2):123-30. doi: 10.1086/653530.
6
Pathophysiology of enteric infections with Giardia duodenalius.十二指肠贾第虫肠道感染的病理生理学
Parasite. 2008 Sep;15(3):261-5. doi: 10.1051/parasite/2008153261.
7
Epidemiological and clinical features of travel-associated cryptosporidiosis.旅行相关隐孢子虫病的流行病学和临床特征。
Clin Microbiol Infect. 2006 Sep;12(9):921-4. doi: 10.1111/j.1469-0691.2006.01487.x.
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Epidemiology of traveler's diarrhea.旅行者腹泻的流行病学
Clin Infect Dis. 2005 Dec 1;41 Suppl 8:S536-40. doi: 10.1086/432948.
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Post-diarrhea chronic intestinal symptoms and irritable bowel syndrome in North American travelers to Mexico.前往墨西哥的北美旅行者腹泻后慢性肠道症状和肠易激综合征
Am J Gastroenterol. 2004 Sep;99(9):1774-8. doi: 10.1111/j.1572-0241.2004.30435.x.
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Case reports: acute hookworm infection: an unusual cause of profuse watery diarrhoea in returned travellers.病例报告:急性钩虫感染:归国旅行者大量水样腹泻的罕见病因。
Trans R Soc Trop Med Hyg. 2003 Jul-Aug;97(4):414-5. doi: 10.1016/s0035-9203(03)90073-3.