World Health Organization, Western Pacific Regional Office, PO Box 2932 (United Nations Avenue), 1000 Manila, Philippines.
World Health Organization, Western Pacific Regional Office, PO Box 2932 (United Nations Avenue), 1000 Manila, Philippines
Hum Reprod. 2015 Apr;30(4):973-86. doi: 10.1093/humrep/deu348. Epub 2015 Feb 3.
What is the contribution of the underuse of modern methods (MM) of contraception to the annual undesired pregnancies in 35 low- and middle-income countries?
Fifteen million out of 16.7 million undesired pregnancies occurring annually in 35 countries could have been prevented with the optimal use of MM of contraception.
Every year, 87 million women worldwide become pregnant unintentionally because of the underuse of MM of contraception.
STUDY DESIGN, SIZE, DURATION: Demographic and health surveys (DHS) of 35 countries, conducted between 2005 and 2012, were analysed.
PARTICIPANTS/MATERIALS, SETTING, METHODS: Contraceptive use of 12 874 unintentionally pregnant women was compared with 111 301 sexually active women who were neither pregnant nor desiring pregnancy.
An average of 96% of 15- to 49-year-old eligible women took part in the survey. When adjusted for covariates and compared with the use of MM of contraception, the use of traditional methods was associated with a 2.7 [95% confidence interval (CI): 2.3-3.4] times increase in odds of an undesired pregnancy, while non-use of any method was associated with a 14.3 (95% CI, 12.3-16.7) times increase. This corresponded to an estimated 16.7 million undesired pregnancies occurring annually in the 35 countries, of which 15.0 million could have been prevented with the optimal use of MM of contraception (13.5 million women did not use MM whilst 1.5 million women utilized MM incorrectly). Women with the lowest educational attainment and wealth quintile were 8.6 (95% CI: 8.2-9.1) and 2.6 (95% CI: 2.4-2.9) times less likely to use contraceptives compared with those with the highest level of each, respectively. Of the 14 893 women who neither desired pregnancy nor used contraception, 5559 (37.3%) cited fear of side effects and health concerns as the reason for non-use, 3331 (22.4%) cited they or their partner's opposition to contraception or religious prohibition and 2620 (17.6%) underestimated the risk of pregnancy.
LIMITATIONS, REASONS FOR CAUTION: Despite the fact that DHS are considered high-quality studies, we should not underestimate the role played by recall bias for past pregnancies. Few women report a current pregnancy in the first trimester and undesired pregnancies at that time are probably prone to under-reporting. Some terminated pregnancies may not be included in the current pregnancy group. Furthermore, covariates measured at the time of the survey may not have reflected the same covariates at the time the currently pregnant women became pregnant.
Underuse of MM of contraception burdens especially the poor and the less educated. National strategies should address unfounded health concerns, fear of side effects, opposition and underestimated risk of pregnancy, which are major contributors to undesired pregnancies.
FUNDING/CONFLICTS OF INTEREST: No external funding was utilized for this report. There are no conflicts of interest to declare.
在 35 个中低收入国家中,现代避孕方法(MM)使用不足对每年意外怀孕的贡献有多大?
在 35 个国家中,每年 1670 万例意外怀孕中有 1500 万例可以通过优化 MM 避孕方法的使用来预防。
每年,全球有 8700 万妇女因 MM 避孕方法使用不足而意外怀孕。
研究设计、大小、持续时间:对 2005 年至 2012 年期间进行的 35 个国家的人口与健康调查(DHS)进行了分析。
参与者/材料、地点、方法:将 12874 名意外怀孕的妇女的避孕使用情况与 111301 名既未怀孕也不希望怀孕的有性行为的妇女进行了比较。
平均有 96%的 15 至 49 岁的合格妇女参加了调查。在调整了协变量并与 MM 避孕方法的使用进行比较后,与使用 MM 避孕方法相比,传统方法的使用与意外怀孕的几率增加了 2.7 倍(95%置信区间[CI]:2.3-3.4),而不使用任何方法与意外怀孕的几率增加了 14.3 倍(95%CI:12.3-16.7)。这相当于在 35 个国家中,每年估计有 1670 万例意外怀孕,其中 1500 万例可以通过优化 MM 避孕方法的使用来预防(1350 万妇女没有使用 MM,而 150 万妇女错误地使用了 MM)。受教育程度和财富最低的五分之一的妇女分别不太可能使用避孕药具,其可能性比每个类别的最高水平的妇女分别低 8.6 倍(95%CI:8.2-9.1)和 2.6 倍(95%CI:2.4-2.9)。在 14893 名既不希望怀孕也不使用避孕药具的妇女中,5559 名(37.3%)妇女表示担心副作用和健康问题是不使用避孕药具的原因,3331 名(22.4%)妇女表示她们或其伴侣反对避孕或宗教禁止,2620 名(17.6%)妇女低估了怀孕的风险。
局限性、谨慎的原因:尽管 DHS 被认为是高质量的研究,但我们不应低估回忆过去怀孕的偏见所起的作用。很少有妇女报告在孕早期怀孕,此时意外怀孕可能容易漏报。一些终止的妊娠可能未包含在当前妊娠组中。此外,在调查时测量的协变量可能无法反映当前怀孕妇女怀孕时的相同协变量。
MM 避孕方法使用不足尤其给贫困和受教育程度较低的人带来了负担。国家战略应解决毫无根据的健康问题、对副作用的恐惧、反对和低估怀孕风险的问题,这些都是意外怀孕的主要原因。
资金/利益冲突:本报告未使用任何外部资金。没有利益冲突需要申报。