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波兰女性口服避孕药最常见的副作用、问题及停药模式:一项横断面研究

The Most Common Side Effects, Concerns and Discontinuation Patterns of Oral Contraceptive Pills Among Polish Women: A Cross-Sectional Study.

作者信息

Karpowicz Natalia, Mączka Katarzyna, Skoczylas Adrian, Pacocha Natalia, Kunicki Michał, Grymowicz Monika, Smolarczyk Roman

机构信息

Department of Gynecological Endocrinology, Clinical Hospital of Duchess Anna Mazowiecka, Medical University of Warsaw, Warsaw, Poland.

Doctoral School, Medical University of Warsaw, Warsaw, Poland.

出版信息

J Family Reprod Health. 2024 Sep;18(3):170-179. doi: 10.18502/jfrh.v18i3.16659.

DOI:10.18502/jfrh.v18i3.16659
PMID:39439736
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11491692/
Abstract

OBJECTIVE

Over the decade, variety and effectiveness of contraception methods have greatly improved, resulting in increased popularity of oral contraceptive pills (OCPs). However, hormonal contraception carries the risk of multiple side effects. The lack of sufficient knowledge often leads to the development of health concerns, which can affect patient's adherence. The aim of our research was to describe a side effect profile of OCPs and assess the most frequent concerns and discontinuation reasons in Polish women. The survey included questions regarding OCPs utilization patterns, side effects, health concerns and attitudes of the responders.

MATERIALS AND METHODS

This cross-sectional study was based on a survey, which was distributed online and open from 29 April to 15 May 2022. The survey included questions regarding OCPs utilization patterns, side effects, health concerns and attitudes of the responders.

RESULTS

Out of 1699 respondents, the current OCPs intake was reported by two thirds of women and 22% had a history of using them in the past. Seventy-nine percent of all OCPs users experienced adverse effects while 9% reported having concerns about safety and potential adverse effects. Decreased libido and weight gain were the most significant reasons for ceasing hormonal contraception. Moreover, the most common concerns and the most unfavorable side effects varied in different age groups. The occurrence of anxiety depended on age and education.

CONCLUSION

Healthcare professionals prescribing OCPs should provide their patients with comprehensive counseling. Understanding and addressing concerns of young women can improve their compliance and reduce the number of unintended pregnancies.

摘要

目的

在过去十年中,避孕方法的种类和有效性有了很大提高,导致口服避孕药(OCPs)的使用更加普遍。然而,激素避孕存在多种副作用风险。知识不足往往会引发健康问题,进而影响患者的依从性。我们研究的目的是描述口服避孕药的副作用概况,并评估波兰女性最常见的担忧和停药原因。该调查包括有关口服避孕药使用模式、副作用、健康担忧以及受访者态度的问题。

材料与方法

这项横断面研究基于一项于2022年4月29日至5月15日在线发布并开放的调查。该调查包括有关口服避孕药使用模式、副作用、健康担忧以及受访者态度的问题。

结果

在1699名受访者中,三分之二的女性报告目前正在服用口服避孕药,22%的女性过去有使用过口服避孕药的经历。所有口服避孕药使用者中有79%经历过不良反应,9%的人表示担心安全性和潜在不良反应。性欲减退和体重增加是停止激素避孕的最主要原因。此外,不同年龄组中最常见的担忧和最不利的副作用各不相同。焦虑的发生取决于年龄和教育程度。

结论

开具口服避孕药处方的医护人员应向患者提供全面的咨询。了解并解决年轻女性的担忧可以提高她们的依从性,并减少意外怀孕的数量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7999/11491692/6a967ba51f13/JFRH-18-170-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7999/11491692/97daf28fe962/JFRH-18-170-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7999/11491692/6a967ba51f13/JFRH-18-170-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7999/11491692/97daf28fe962/JFRH-18-170-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7999/11491692/6a967ba51f13/JFRH-18-170-g002.jpg

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Risk of venous thromboembolism during the use of oral estrogen-progestogen hormone therapies in light of most recent research findings.根据最新研究结果,口服雌激素 - 孕激素激素疗法使用期间静脉血栓栓塞的风险
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