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傅里叶域光学相干断层扫描对泪点和垂直泪小管的三维及正面成像:迈向建立正常数据库的一步。

Fourier Domain Optical Coherence Tomography With 3D and En Face Imaging of the Punctum and Vertical Canaliculus: A Step Toward Establishing a Normative Database.

作者信息

Kamal Saurabh, Ali Mohammad Javed, Ali Mohammad Hasnat, Naik Milind N

机构信息

*Dacryology Service and †Biostatistics Service, L. V. Prasad Eye Institute, Hyderabad, India.

出版信息

Ophthalmic Plast Reconstr Surg. 2016 May-Jun;32(3):170-3. doi: 10.1097/IOP.0000000000000396.

Abstract

PURPOSE

To report the features of Fourier domain optical coherence tomography imaging of the normal punctum and vertical canaliculus.

METHODS

Prospective, interventional series of consecutive healthy and asymptomatic adults, who volunteered for optical coherence tomography imaging, were included in the study. Fourier domain optical coherence tomography images of the punctum and vertical canaliculus along with 3D and En face images were captured using the RTVue scanner with a corneal adaptor module and a wide-angled lens. Maximum punctal diameter, mid-canalicular diameter, and vertical canalicular height were calculated. Statistical analysis was performed using Pearson correlation test, and scatter plot matrices were analyzed.

RESULTS

A total of 103 puncta of 52 healthy subjects were studied. Although all the images could depict the punctum and vertical canaliculus and all the desired measurements could be obtained, occasional tear debris within the canaliculus was found to be interfering with the imaging. The mean maximum punctal diameter, mid-canalicular diameter, and vertical canalicular height were recorded as 214.71 ± 73 μm, 125.04 ± 60.69 μm, and 890.41 ± 154.76 μm, respectively, with an insignificant correlation between them. The maximum recorded vertical canalicular height in all the cases was far less than the widely reported depth of 2 mm. High-resolution 3D and En face images provided a detailed topography of punctal surface and overview of vertical canaliculus.

CONCLUSION

Fourier domain optical coherence tomography with 3D and En face imaging is a useful noninvasive modality to image the proximal lacrimal system with consistently reproducible high-resolution images. This is likely to help clinicians in the management of proximal lacrimal disorders.

摘要

目的

报告正常泪点和垂直泪小管的傅里叶域光学相干断层扫描成像特征。

方法

本研究纳入了连续的健康无症状成年人,他们自愿接受光学相干断层扫描成像,为前瞻性干预系列研究。使用配备角膜适配器模块和广角镜头的RTVue扫描仪采集泪点和垂直泪小管的傅里叶域光学相干断层扫描图像以及三维(3D)和正面图像。计算泪点最大直径、泪小管中部直径和垂直泪小管高度。采用Pearson相关检验进行统计分析,并分析散点图矩阵。

结果

共研究了52名健康受试者的103个泪点。尽管所有图像均可描绘泪点和垂直泪小管,且能获得所有所需测量值,但发现泪小管内偶尔出现的泪液碎屑会干扰成像。记录的泪点平均最大直径、泪小管中部直径和垂直泪小管高度分别为214.71±73μm、125.04±60.69μm和890.41±154.76μm,它们之间的相关性不显著。所有病例中记录的最大垂直泪小管高度远小于广泛报道的2mm深度。高分辨率3D和正面图像提供了泪点表面的详细地形图和垂直泪小管的概况。

结论

具有3D和正面成像功能的傅里叶域光学相干断层扫描是一种有用的非侵入性检查方法,可对近端泪道系统进行成像,获得具有一致可重复性的高分辨率图像。这可能有助于临床医生管理近端泪道疾病。

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