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[正常成年人泪小点光学相干断层扫描的初步研究]

[A preliminary study on optical coherence tomography of the lacrimal punctum in normal adults].

作者信息

Wang Y S, Tao H, Wang H B, Wang F, Dong W L

机构信息

Lacrimal Center of Ophthalmology, Third Medical Center of PLA General Hospital, Beijing 100039, China (working at Department of Ophthalmology, Affiliated Hospital of Chengde Medical College, Chengde 067000, China).

Lacrimal Center of Ophthalmology, Third Medical Center of PLA General Hospital, Beijing 100039, China.

出版信息

Zhonghua Yan Ke Za Zhi. 2019 Sep 11;55(9):695-699. doi: 10.3760/cma.j.issn.0412-4081.2019.09.012.

Abstract

To study the imaging characteristics and accumulate data of optical coherence tomography (OCT) of the lacrimal punctum in normal adults. From September to November 2018, 59 healthy adults (90 eyes) with normal lacrimal punctum structure were enrolled in this cross-sectional study conducted at the Lacrimal Center of Ophthalmology, Third Medical Center of PLA General Hospital, including 21 males (34 eyes) and 38 females (56 eyes), aged 18-65 years. All the subjects were examined by slit lamp microscopy to measure the maximum transverse diameter. OCT was performed to observe the inferior lacrimal punctum, including the external punctal diameter, the punctal diameter at 100 μm and 200 μm depth. The difference in the diameter of different parts of the punctum was analyzed. Independent sample test and single factor analysis of variance were used for statistical analysis. In normal adults, the maximum transverse diameter under a slit lamp was (545.6±149.3) μm, the external punctal diameter on OCT images was (548.4±130.5) μm, and the punctal width at 100 μm and 200 μm depth on OCT images was (262.8±120.8) μm and (179.2±110.0) μm, respectively. There was no significant difference between the maximum transverse diameter of the punctum under a slit lamp microscope and the OCT outer diameter of the punctum (0.133, 0.894). There were significant differences between the diameter of the lacrimal punctum in the different scanning sites of the OCT (213.237, 0.01). There was significant difference between the punctal width at 100 μm and the external punctal diameter on OCT images (15.229, 0.01). There was significant difference between the punctal width at 200 μm and the external punctal diameter on OCT images (20.517, 0.01). There was significant difference between the punctal width at 100 μm and 200 μm depth on OCT images (4.855, 0.01). The width of different parts of the lacrimal punctum in healthy adults is different on OCT images, and the punctal width at 200 μm depth is the narrowest. .

摘要

研究正常成年人泪小点的光学相干断层扫描(OCT)成像特征并积累相关数据。2018年9月至11月,选取解放军总医院第三医学中心眼科泪器中心59例(90眼)泪小点结构正常的健康成年人纳入本横断面研究,其中男性21例(34眼),女性38例(56眼),年龄18 - 65岁。所有受试者均行裂隙灯显微镜检查测量泪小点最大横径。采用OCT观察下泪小点,测量其外口直径、100μm及200μm深度处的泪小点直径。分析泪小点不同部位直径的差异。采用独立样本t检验和单因素方差分析进行统计学分析。正常成年人裂隙灯下泪小点最大横径为(545.6±149.3)μm,OCT图像上泪小点外口直径为(548.4±130.5)μm,OCT图像上100μm及200μm深度处泪小点宽度分别为(262.8±120.8)μm和(179.2±110.0)μm。裂隙灯下泪小点最大横径与OCT图像上泪小点外径比较,差异无统计学意义(0.133,0.894)。OCT不同扫描部位泪小点直径比较,差异有统计学意义(213.237,0.01)。OCT图像上100μm深度处泪小点宽度与泪小点外口直径比较,差异有统计学意义(15.229,0.01)。OCT图像上200μm深度处泪小点宽度与泪小点外口直径比较,差异有统计学意义(20.517,0.01)。OCT图像上100μm与200μm深度处泪小点宽度比较,差异有统计学意义(4.855,0.01)。健康成年人泪小点不同部位在OCT图像上宽度不同,200μm深度处泪小点宽度最窄。

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