Cho Tracey A
Continuum (Minneap Minn). 2015 Feb;21(1 Spinal Cord Disorders):13-35. doi: 10.1212/01.CON.0000461082.25876.4a.
This article reviews the neuroanatomical arrangement of the white matter pathways and gray matter columns of the spinal cord and explores how injury to the spinal cord leads to a typical constellation of symptoms and signs depending on the cross-sectional and longitudinal extent of the lesion.
As refined imaging techniques and novel biomarkers help identify spinal cord diseases more readily, familiarity with the classic spinal cord syndromes and localizing principles remains essential for prompt recognition of spinal cord involvement and efficient diagnostic testing in order to direct therapy and avoid permanent injury.
Spinal cord disease can progress rapidly and cause debilitating deficits, making prompt recognition and treatment crucial. Knowledge of the organization of these pathways and cell columns, along with their surrounding structures and blood supply, allows the clinician to localize processes within the spinal column. This, in turn, can suggest the type of pathologic process involved and direct further evaluation and management.
本文回顾脊髓白质通路和灰质柱的神经解剖学结构，并探讨脊髓损伤如何根据病变的横截面积和纵向范围导致一系列典型的症状和体征。
随着先进的成像技术和新型生物标志物有助于更轻松地识别脊髓疾病，熟悉经典的脊髓综合征和定位原则对于及时识别脊髓受累情况以及进行有效的诊断测试以指导治疗并避免永久性损伤仍然至关重要。
脊髓疾病可能迅速进展并导致使人衰弱的功能缺陷，因此及时识别和治疗至关重要。了解这些通路和细胞柱的组织结构，以及它们周围的结构和血液供应情况，可使临床医生对脊柱内的病变进行定位。反过来，这可以提示所涉及的病理过程类型，并指导进一步的评估和管理。
