Gupta N, Garg U C, Dhand R, Kaur A, Ganguly N K
Department of Experimental Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Enzyme. 1989;41(2):108-11. doi: 10.1159/000469061.
Bronchoalveolar lavage (BALF) was found to be a useful index of cell damage. It has been observed that the enzymes in BALF could give an idea of cell damage in a pulmonary disease. Acid phosphatase, alkaline phosphatase, leucine aminopeptidase and gamma-glutamyl-transpeptidase were assessed in mild, moderate, and severe pulmonary tuberculosis patients and Mantoux-negative normal controls. Activities of these enzymes were found to be higher in patients and were increasing with the severity of the disease. Increase in these enzymes in pulmonary tuberculosis patients could be attributed to lung tissue damage.
支气管肺泡灌洗（BALF）被发现是细胞损伤的一个有用指标。据观察，BALF中的酶可以反映肺部疾病中的细胞损伤情况。对轻度、中度和重度肺结核患者以及结核菌素试验阴性的正常对照者进行了酸性磷酸酶、碱性磷酸酶、亮氨酸氨肽酶和γ-谷氨酰转肽酶的评估。发现这些酶的活性在患者中较高，并且随着疾病的严重程度而增加。肺结核患者中这些酶的增加可能归因于肺组织损伤。
