Department of Orthopedic Surgery, Mayo Clinic, 200 First Street SW, Gonda 14, Rochester, MN 55905. E-mail address for A.D. Hanssen:
J Bone Joint Surg Am. 2015 Feb 4;97(3):216-23. doi: 10.2106/JBJS.N.00540.
Severe metaphyseal and meta-diaphyseal bone loss poses important challenges in revision total knee arthroplasty. The best strategy for addressing massive tibial bone loss has not been determined. The purpose of this study was to assess the intermediate-term clinical and radiographic results of porous tibial cone implantation.
Sixty-six porous tantalum tibial cones (sixty-three patients) were reviewed at a mean follow-up time of seventy months (range, sixty to 106 months). According to the Anderson Orthopaedic Research Institute bone defect classification, twenty-four knees had a Type-3 defect, twenty-five knees had a Type-2B defect, and seventeen knees had a Type-2A defect.
The mean age at the time of the index revision was sixty-seven years (range, forty-one to eighty-three years), and 57% of patients were female. The mean American Society of Anesthesiologists Physical Status was 2.4 (range, 2 to 3), and the mean body mass index was 33 kg/m(2) (range, 25 to 53 kg/m(2)). Fifteen patients (24%) were on immunosuppressant medications, and eight patients (13%) were current smokers. The patients underwent a mean number of 3.4 prior knee surgical procedures (range, one to twenty procedures), and 49% of patients (thirty-one patients) had a history of periprosthetic infection. The mean Knee Society Scores improved significantly from 55 points preoperatively (range, 4 to 97 points) to 80 points (range, 28 to 100 points) at the time of the latest follow-up (p < 0.0001). One patient had progressive radiolucencies about the tibial stem and cone on radiographs. One patient had complete radiolucencies about the tibial cone, concerning for fibrous ingrowth. Three other cones were revised: one for infection, one for aseptic loosening, and one for periprosthetic fracture. Revision-free survival of the tibial cone component was >95% at the time of the latest follow-up.
Porous tantalum tibial cones offer a promising management option for severe tibial bone loss. At the intermediate-term follow-up (five to nine years), porous tantalum tibial cones had durable clinical results and radiographic fixation. The biologic ingrowth of these implants offers the potential for successful long-term structural support in complex knee reconstruction.
严重的干骺端和骨干骨丢失给翻修全膝关节置换术带来了重要挑战。处理大量胫骨骨丢失的最佳策略尚未确定。本研究的目的是评估多孔胫骨锥植入的中期临床和影像学结果。
在平均 70 个月(60 至 106 个月)的随访时,对 66 个多孔钽胫骨锥(63 例患者)进行了回顾性分析。根据安德森骨科研究所在骨缺损分类,24 例膝关节为 3 型缺损,25 例膝关节为 2B 型缺损,17 例膝关节为 2A 型缺损。
指数翻修时的平均年龄为 67 岁(41 至 83 岁),57%的患者为女性。美国麻醉医师协会身体状况平均为 2.4(范围 2 至 3),平均体重指数为 33kg/m²(范围 25 至 53kg/m²)。15 例(24%)患者正在服用免疫抑制剂,8 例(13%)患者为当前吸烟者。患者平均进行了 3.4 次膝关节手术(范围为 1 至 20 次),49%(31 例)的患者有假体周围感染史。术前膝关节协会评分平均为 55 分(范围为 4 至 97 分),末次随访时提高至 80 分(范围为 28 至 100 分)(p < 0.0001)。1 例患者胫骨柄和胫骨锥的影像学上出现了进行性透亮线。1 例患者胫骨锥完全透亮,考虑为纤维性植入物。其他 3 个胫骨锥进行了翻修:1 例因感染,1 例因无菌性松动,1 例因假体周围骨折。末次随访时,胫骨锥组件的无翻修生存率>95%。
多孔钽胫骨锥为严重胫骨骨丢失提供了一种有前途的治疗选择。在中期随访(5 至 9 年)时,多孔钽胫骨锥具有持久的临床效果和影像学固定。这些植入物的生物性植入物具有为复杂膝关节重建提供成功长期结构性支撑的潜力。