Suvarna Gayatri Sheena, Nadiger Ramesh Khandurao, Guttal Satyabodh Shesharaj, Shetty Omkar
Senior Lecturer, Department of Prosthodontics, Dr D.Y.Patil Dental College and Hospital , Navi Mumbai, Maharashtra, India .
Professor, Department of Prosthodontics and Implantology, S.D.M College of Dental Sciences and Hospital , Dharwad, Karnataka, India .
J Clin Diagn Res. 2014 Dec;8(12):ZD08-10. doi: 10.7860/JCDR/2014/9446.5250. Epub 2014 Dec 5.
Deficiency of the alkaline phosphatase isoenzyme can lead to a rare hereditary disorder called Hypophosphatasia. It is characterized by defective mineralization of the skeletal and dental structures of the body. Hypophophatasia is classified into six clinical forms namely, perinatal lethal, perinatal benign, infantile, childhood, adult and odontohypophosphatasia. This clinical report describes the prosthetic rehabilitation of an 18-year-old girl with Hypophosphatasia with partial anodontia and no occlusion. A precision attachment retained unconventional removable partial denture in the maxillary arch and conventional removable partial denture in the mandibular were fabricated to establish an acceptable masticatory function, speech, occlusion and aesthetics for the patient.
碱性磷酸酶同工酶缺乏可导致一种罕见的遗传性疾病，称为低磷酸酯酶症。其特征是身体骨骼和牙齿结构矿化不良。低磷酸酯酶症分为六种临床类型，即围产期致死型、围产期良性型、婴儿型、儿童型、成人型和牙型低磷酸酯酶症。本临床报告描述了一名患有低磷酸酯酶症、部分牙缺失且无咬合关系的18岁女孩的修复治疗。制作了上颌采用精密附着体固位的非常规可摘局部义齿和下颌常规可摘局部义齿，以建立患者可接受的咀嚼功能、言语功能、咬合关系和美观效果。
