Çakmur Hülya, Derviş Emine
University of Kafkas, School of Medicine, Department of Dermatology, Kars, Turkey.
Eur J Dermatol. 2015 Apr;25(2):169-76. doi: 10.1684/ejd.2014.2511.
Patients with psoriasis experience a low quality of life and high treatment burden:
To assess psoriatic patient quality of life using the Dermatology Life Quality Index (DLQI) in the Northeastern Anatolia region of Turkey. Additionally, we evaluated the correlation between the DLQI and the clinical severity of psoriasis and examined demographic data and their relationship with the DLQI and psoriasis severity:
This study was a single-center, prospective, cross-sectional study at the University of Kafkas, Kars, Turkey. 127 adult patients were included in the study. The Turkish version of the DLQI was used. To measure psoriasis severity, the Psoriasis Area Severity Index (PASI) and Body Surface Area (BSA) were simultaneously evaluated. The patient demographics were compared with quality of life and the severity of psoriasis:
DLQI scores ranged from "very large" to "extremely large" in 61% of the patients. The psoriasis severity (BSA and PASI) was "mild" in 63% of patients. The quality of life was significantly affected in cigarette smokers and in patients whose disease included nail involvement. The PASI and BSA scores of patients with scalp and nail involvement were significantly higher. A significant, positive correlation was found between disease duration and the severity of psoriasis. BSA correlated with PASI:
The quality of life of psoriasis patients is strongly reduced. A significant relationship was found for DLQI with nail psoriasis and smoking. A linear, positive correlation was detected between the DLQI and BSA but not between the DLQI and PASI.
银屑病患者生活质量低下且治疗负担沉重。
使用皮肤病生活质量指数(DLQI)评估土耳其安纳托利亚东北部地区银屑病患者的生活质量。此外,我们评估了DLQI与银屑病临床严重程度之间的相关性,并检查了人口统计学数据及其与DLQI和银屑病严重程度的关系。
本研究是在土耳其卡尔斯的卡夫卡大学进行的单中心、前瞻性横断面研究。127名成年患者纳入研究。使用DLQI的土耳其语版本。为测量银屑病严重程度,同时评估银屑病面积和严重程度指数(PASI)及体表面积(BSA)。将患者人口统计学数据与生活质量和银屑病严重程度进行比较。
61%的患者DLQI评分范围为“非常大”至“极其大”。63%的患者银屑病严重程度(BSA和PASI)为“轻度”。吸烟者以及疾病累及指甲的患者生活质量受到显著影响。头皮和指甲受累患者的PASI和BSA评分显著更高。发现病程与银屑病严重程度之间存在显著正相关。BSA与PASI相关。
银屑病患者的生活质量严重降低。发现DLQI与指甲银屑病和吸烟之间存在显著关系。检测到DLQI与BSA之间存在线性正相关,但DLQI与PASI之间不存在。