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种族差异:利用步行速度识别有健康不良后果风险的社区居住女性——骨关节炎倡议研究

Race Differences: Use of Walking Speed to Identify Community-Dwelling Women at Risk for Poor Health Outcomes--Osteoarthritis Initiative Study.

作者信息

Kirkness Carmen S, Ren Jinma

机构信息

C.S. Kirkness, PT, PhD, Department of Internal Medicine, Center for Outcomes Research, University of Illinois College of Medicine at Peoria, One Illini Dr, Box 1649, Peoria, IL 61656 (USA).

J. Ren, PhD, Department of Internal Medicine, Center for Outcomes Research, University of Illinois College of Medicine at Peoria.

出版信息

Phys Ther. 2015 Jul;95(7):955-65. doi: 10.2522/ptj.20140028. Epub 2015 Feb 5.

Abstract

BACKGROUND

Onset of disability, risk for future falls, frailty, functional decline, and mortality are strongly associated with a walking speed of less than 1.0 m/s.

OBJECTIVE

The study objective was to determine whether there were differences in slow walking speed (<1.0 m/s) between community-dwelling African American and white American adult women with osteoarthritis symptoms. An additional aim was to examine whether racial differences in walking speed can be attributed to age, obesity, socioeconomic factors, disease severity, or comorbidities.

DESIGN

A cross-sectional design was used.

METHODS

Community-dwelling adults were recruited from Baltimore, Maryland; Columbus, Ohio; Pittsburgh, Pennsylvania; and Pawtucket, Rhode Island. Participants were 2,648 women (23% African American) who were 45 to 79 years of age and had a self-selected baseline walking speed of 20 m/s in the Osteoarthritis Initiative Study. Mixed-effects logistic regression models were used to examine racial differences in walking speed (<1.0 m/s versus ≥1.0 m/s), with adjustments for demographic factors, socioeconomic factors, disease severity, and comorbidities.

RESULTS

Walking speed was significantly slower for African American women than for white American women (mean walking speed=1.19 and 1.33 m/s, respectively). The prevalence of a walking speed of less than 1.0 m/s in this cohort of middle-aged women was 9%; about 50% of the women with a walking speed of less than 1.0 m/s were younger than 65 years. Women with a walking speed of less than 1.0 m/s had lower values for socioeconomic factors, higher values for disease severity, and higher prevalences of obesity and comorbidities than those with a walking speed of ≥1.0 m/s. After controlling for these covariates, it was found that African American women were 3 times (odds ratio=2.9; 95% confidence interval=2.0, 4.1) more likely to have a walking speed of less than 1.0 m/s than white American women.

LIMITATIONS

The study design made it impossible to know whether a walking speed of less than 1.0 m/s in women who were 45 years of age or older was a predictor of future poor health outcomes.

CONCLUSIONS

In this study, race was independently associated with a walking speed of less than 1.0 m/s in community-dwelling women who had or were at risk for osteoarthritis, with African American women having 3 times the risk for slow walking as white American women. This finding suggests that middle-aged African American women have an increased risk for poor health outcomes. Further longitudinal evaluations are needed to confirm the long-term health outcomes in a middle-aged population and to establish walking speed as a useful tool for identifying middle-aged women at high risk for poor health outcomes.

摘要

背景

残疾的发生、未来跌倒的风险、身体虚弱、功能衰退和死亡率与步行速度低于1.0米/秒密切相关。

目的

本研究的目的是确定有骨关节炎症状的非裔美国和美国白人成年社区女性在步行速度较慢(<1.0米/秒)方面是否存在差异。另一个目的是研究步行速度的种族差异是否可归因于年龄、肥胖、社会经济因素、疾病严重程度或合并症。

设计

采用横断面设计。

方法

从马里兰州巴尔的摩、俄亥俄州哥伦布、宾夕法尼亚州匹兹堡和罗德岛州波塔基特招募社区成年居民。参与者为2648名年龄在45至79岁之间的女性(23%为非裔美国人),她们在骨关节炎倡议研究中的自我选择基线步行速度为20米/秒。使用混合效应逻辑回归模型来研究步行速度(<1.0米/秒与≥1.0米/秒)的种族差异,并对人口统计学因素、社会经济因素、疾病严重程度和合并症进行调整。

结果

非裔美国女性的步行速度明显慢于美国白人女性(平均步行速度分别为1.19米/秒和1.33米/秒)。在这一中年女性队列中,步行速度低于1.0米/秒的患病率为9%;步行速度低于1.0米/秒的女性中约50%年龄小于65岁。与步行速度≥1.0米/秒的女性相比,步行速度低于1.0米/秒的女性社会经济因素值较低,疾病严重程度值较高,肥胖和合并症的患病率也较高。在控制了这些协变量后,发现非裔美国女性步行速度低于1.0米/秒的可能性是美国白人女性的3倍(优势比=2.9;95%置信区间=2.0,4.1)。

局限性

该研究设计无法确定45岁及以上女性步行速度低于1.0米/秒是否是未来健康状况不佳的预测指标。

结论

在本研究中,种族与有骨关节炎或有骨关节炎风险的社区女性步行速度低于1.0米/秒独立相关,非裔美国女性步行速度慢的风险是美国白人女性的3倍。这一发现表明中年非裔美国女性健康状况不佳的风险增加。需要进一步的纵向评估来确认中年人群的长期健康结果,并将步行速度确立为识别健康状况不佳高风险中年女性的有用工具。

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