Franken Matthias K, Hagoort Peter, Acheson Daniel J
Max Planck Institute for Psycholinguistics, P.O. Box 310, 6500 AH Nijmegen, The Netherlands; Radboud University Nijmegen, Donders Institute for Brain, Cognition and Behaviour, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.
Max Planck Institute for Psycholinguistics, P.O. Box 310, 6500 AH Nijmegen, The Netherlands; Radboud University Nijmegen, Donders Institute for Brain, Cognition and Behaviour, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.
Brain Lang. 2015 Mar;142:18-23. doi: 10.1016/j.bandl.2015.01.001. Epub 2015 Feb 2.
Models of speech production explain event-related suppression of the auditory cortical response as reflecting a comparison between auditory predictions and feedback. The present MEG study was designed to test two predictions from this framework: (1) whether the reduced auditory response varies as a function of the mismatch between prediction and feedback; (2) whether individual variation in this response is predictive of speech-motor adaptation. Participants alternated between online imitation and listening tasks. In the imitation task, participants began each trial producing the same vowel (/e/) and subsequently listened to and imitated auditorily-presented vowels varying in acoustic distance from /e/. Results replicated suppression, with a smaller M100 during speaking than listening. Although we did not find unequivocal support for the first prediction, participants with less M100 suppression were better at the imitation task. These results are consistent with the enhancement of M100 serving as an error signal to drive subsequent speech-motor adaptation.
言语产生模型将听觉皮层反应的事件相关抑制解释为反映听觉预测与反馈之间的比较。本项脑磁图（MEG）研究旨在检验该框架的两个预测：（1）听觉反应的降低是否随预测与反馈之间的不匹配而变化；（2）这种反应的个体差异是否可预测言语运动适应。参与者在在线模仿和听力任务之间交替进行。在模仿任务中，参与者在每次试验开始时发出相同的元音（/e/），随后听取并模仿与/e/在声学距离上不同的听觉呈现元音。结果重复了抑制现象，即说话时的M100比听力时小。虽然我们没有找到对第一个预测的确凿支持，但M100抑制较少的参与者在模仿任务中表现更好。这些结果与M100增强作为驱动后续言语运动适应的误差信号一致。
