耻垢分枝杆菌实验室菌株（MC2 155）及异烟肼耐药（4XR1/R2）突变菌株的全基因组序列
Complete Genome Sequences of a Mycobacterium smegmatis Laboratory Strain (MC2 155) and Isoniazid-Resistant (4XR1/R2) Mutant Strains.
作者信息
Mohan Abhilash, Padiadpu Jyothi, Baloni Priyanka, Chandra Nagasuma
机构信息
Department of Biochemistry, IISc, Bangalore, India.
Department of Biochemistry, IISc, Bangalore, India
出版信息
Genome Announc. 2015 Feb 5;3(1):e01520-14. doi: 10.1128/genomeA.01520-14.
Abstract
We report the whole genome sequences of a Mycobacterium smegmatis laboratory wild-type strain (MC(2) 155) and mutants (4XR1, 4XR2) resistant to isoniazid. Compared to Mycobacterium smegmatis MC(2) 155 (NC_008596), a widely used strain in laboratory experiments, the MC(2) 155, 4XR1, and 4XR2 strains are 60, 128 and 93 bp longer, respectively.
摘要
我们报告了耻垢分枝杆菌实验室野生型菌株（MC(2) 155）及对异烟肼耐药的突变体（4XR1、4XR2）的全基因组序列。与实验室实验中广泛使用的耻垢分枝杆菌MC(2) 155（NC_008596）相比，MC(2) 155、4XR1和4XR2菌株分别长60、128和93碱基对。
相似文献
1
Complete Genome Sequences of a Mycobacterium smegmatis Laboratory Strain (MC2 155) and Isoniazid-Resistant (4XR1/R2) Mutant Strains.耻垢分枝杆菌实验室菌株（MC2 155）及异烟肼耐药（4XR1/R2）突变菌株的全基因组序列
Genome Announc. 2015 Feb 5;3(1):e01520-14. doi: 10.1128/genomeA.01520-14.
2
Draft Genome Sequence of mc251, a Highly Hydrogen Peroxide-Resistant Mycobacterium smegmatis Mutant Strain.耻垢分枝杆菌过氧化氢高抗性突变株mc251的基因组序列草图
Genome Announc. 2014 Feb 20;2(1):e00092-14. doi: 10.1128/genomeA.00092-14.
3
Gene expression profiles of wild-type and isoniazid-resistant strains of Mycobacterium smegmatis.耻垢分枝杆菌野生型和异烟肼耐药菌株的基因表达谱
Data Brief. 2015 May 27;4:186-9. doi: 10.1016/j.dib.2015.05.006. eCollection 2015 Sep.
4
Complete Genome Sequences of an Escherichia coli Laboratory Strain and Trimethoprim-Resistant (TMP32XR) Mutant Strains.一株大肠杆菌实验室菌株及耐甲氧苄啶（TMP32XR）突变菌株的全基因组序列
Genome Announc. 2015 Dec 10;3(6):e01434-15. doi: 10.1128/genomeA.01434-15.
5
Roles of the three Mycobacterium smegmatis katG genes for peroxide detoxification and isoniazid susceptibility.耻垢分枝杆菌三个katG基因在过氧化物解毒及对异烟肼敏感性方面的作用
Microbiol Immunol. 2018 Mar;62(3):158-167. doi: 10.1111/1348-0421.12574.
6
Disruption of adhC reveals a large duplication in the Mycobacterium smegmatis mc(2)155 genome.adhC基因的破坏揭示了耻垢分枝杆菌mc(2)155基因组中的一个大的重复序列。
Microbiology (Reading). 2001 Dec;147(Pt 12):3281-94. doi: 10.1099/00221287-147-12-3281.
7
Purification and characterization of dihydrofolate reductase from wild-type and trimethoprim-resistant Mycobacterium smegmatis.耻垢分枝杆菌野生型和甲氧苄啶耐药型二氢叶酸还原酶的纯化与鉴定
Exp Parasitol. 1991 Feb;72(2):184-90. doi: 10.1016/0014-4894(91)90136-k.
8
Mycobacterium smegmatis MSMEG_3705 encodes a selective major facilitator superfamily efflux pump with multiple roles.耻垢分枝杆菌MSMEG_3705编码一种具有多种功能的选择性主要易化子超家族外排泵。
Curr Microbiol. 2015 Jun;70(6):801-9. doi: 10.1007/s00284-015-0783-0. Epub 2015 Feb 20.
9
A rapid viability and drug-susceptibility assay utilizing mycobacteriophage as an indicator of drug susceptibilities of Anti-TB drugs against mc 155.一种利用分枝杆菌噬菌体作为抗结核药物对mc 155药敏指标的快速生存力和药敏试验。
Int J Mycobacteriol. 2019 Apr-Jun;8(2):124-131. doi: 10.4103/ijmy.ijmy_47_19.
10
Gene and whole genome analyses reveal that the mycobacterial strain JS623 is not a member of the species Mycobacterium smegmatis.基因和全基因组分析表明，分枝杆菌菌株JS623不是耻垢分枝杆菌物种的成员。
Microb Biotechnol. 2016 Mar;9(2):269-74. doi: 10.1111/1751-7915.12336. Epub 2016 Feb 1.
引用本文的文献
1
Detection of with IS loop-mediated isothermal amplification and a fluorescent reporter probe.使用IS环介导等温扩增法和荧光报告探针检测……（原文内容不完整，无法准确完整翻译）
Appl Environ Microbiol. 2025 May 21;91(5):e0027025. doi: 10.1128/aem.00270-25. Epub 2025 Apr 16.
2
Evaluation of the Anti-Mycobacterial and Anti-Inflammatory Activities of the New Cardiotonic Steroid γ-Benzylidene Digoxin-15 in Macrophage Models of Infection.新型强心甾类化合物γ-亚苄基地高辛-15在感染巨噬细胞模型中的抗分枝杆菌及抗炎活性评价
Microorganisms. 2025 Jan 25;13(2):269. doi: 10.3390/microorganisms13020269.
3
How macrophage heterogeneity affects tuberculosis disease and therapy.巨噬细胞的异质性如何影响结核病及治疗。
Nat Rev Immunol. 2025 May;25(5):370-384. doi: 10.1038/s41577-024-01124-3. Epub 2025 Jan 7.
4
Genome Sequence of the Bacteriophage Eugenia.噬菌体番樱桃的基因组序列
MicroPubl Biol. 2024 Dec 14;2024. doi: 10.17912/micropub.biology.001401. eCollection 2024.
5
Genetic stability of under the stress of first-line antitubercular agents.一线抗结核药物压力下 的遗传稳定性。
Elife. 2024 Nov 20;13:RP96695. doi: 10.7554/eLife.96695.
6
A Novel Bi-Directional Channel for Nutrient Uptake across Mycobacterial Outer Envelope.一种跨分枝杆菌外膜摄取营养物质的新型双向通道。
Microorganisms. 2024 Sep 4;12(9):1827. doi: 10.3390/microorganisms12091827.
7
A low-cost and versatile paramagnetic bead DNA extraction method for environmental surveillance.一种低成本、多功能的用于环境监测的顺磁珠 DNA 提取方法。
Appl Environ Microbiol. 2024 Oct 23;90(10):e0102124. doi: 10.1128/aem.01021-24. Epub 2024 Sep 10.
8
Complete genome sequences and characteristics of mycobacteriophages Diminimus, Dulcita, Glaske16, and Koreni.分枝杆菌噬菌体Diminimus、Dulcita、Glaske16和Koreni的全基因组序列及特征
Microbiol Resour Announc. 2024 Jan 17;13(1):e0101023. doi: 10.1128/MRA.01010-23. Epub 2023 Dec 8.
9
Identification and characterization of endo-α-, exo-α-, and exo-β-D-arabinofuranosidases degrading lipoarabinomannan and arabinogalactan of mycobacteria.鉴定和特性分析能够降解分枝杆菌脂阿拉伯甘露聚糖和阿拉伯半乳聚糖的内-α-、外-α-和外-β-D-阿拉伯呋喃糖苷酶。
Nat Commun. 2023 Sep 19;14(1):5803. doi: 10.1038/s41467-023-41431-2.
10
Gene expression during the development of Mycobacterium smegmatis biofilms on hydroxyapatite surfaces.分枝杆菌在羟基磷灰石表面生物膜发育过程中的基因表达。
Int Microbiol. 2024 Feb;27(1):257-263. doi: 10.1007/s10123-023-00385-7. Epub 2023 Jun 13.
本文引用的文献
1
Trimmomatic: a flexible trimmer for Illumina sequence data.Trimmomatic：一款适用于 Illumina 测序数据的灵活修剪工具。
Bioinformatics. 2014 Aug 1;30(15):2114-20. doi: 10.1093/bioinformatics/btu170. Epub 2014 Apr 1.
2
New antituberculosis drugs, regimens, and adjunct therapies: needs, advances, and future prospects.新型抗结核药物、方案和辅助治疗：需求、进展和未来前景。
Lancet Infect Dis. 2014 Apr;14(4):327-40. doi: 10.1016/S1473-3099(13)70328-1.
3
Bacterial evolution of antibiotic hypersensitivity.抗生素过敏的细菌进化。
Mol Syst Biol. 2013 Oct 29;9:700. doi: 10.1038/msb.2013.57.
4
Comparative analysis of Mycobacterium and related Actinomycetes yields insight into the evolution of Mycobacterium tuberculosis pathogenesis.对分枝杆菌和相关放线菌的比较分析为结核分枝杆菌发病机制的进化提供了深入了解。
BMC Genomics. 2012 Mar 28;13:120. doi: 10.1186/1471-2164-13-120.
5
Fast gapped-read alignment with Bowtie 2.快速缺口读对准与 Bowtie 2。
Nat Methods. 2012 Mar 4;9(4):357-9. doi: 10.1038/nmeth.1923.
6
RATT: Rapid Annotation Transfer Tool.RATT：快速注释转移工具。
Nucleic Acids Res. 2011 May;39(9):e57. doi: 10.1093/nar/gkq1268. Epub 2011 Feb 8.
7
The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data.基因组分析工具包：一种用于分析下一代 DNA 测序数据的 MapReduce 框架。
Genome Res. 2010 Sep;20(9):1297-303. doi: 10.1101/gr.107524.110. Epub 2010 Jul 19.
8
Laboratory maintenance of Mycobacterium smegmatis.耻垢分枝杆菌的实验室保存
Curr Protoc Microbiol. 2009 Aug;Chapter 10:Unit10C.1. doi: 10.1002/9780471729259.mc10c01s14.
9
Accelerated evolution of resistance in multidrug environments.多药环境中耐药性的加速演变。
Proc Natl Acad Sci U S A. 2008 Sep 16;105(37):13977-81. doi: 10.1073/pnas.0805965105. Epub 2008 Sep 8.
10
SNPeffect: a database mapping molecular phenotypic effects of human non-synonymous coding SNPs.SNPeffect：一个映射人类非同义编码单核苷酸多态性分子表型效应的数据库。
Nucleic Acids Res. 2005 Jan 1;33(Database issue):D527-32. doi: 10.1093/nar/gki086.
Zotero 插件