神经化先天性黑素细胞痣，类似色素性神经纤维瘤。

Singh Nidhi, Chandrashekar Laxmisha, Kar Rakhee, Sylvia Mary Theresa, Thappa Devinder Mohan

Department of Dermatology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.

Department of Pathology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.

Indian J Dermatol. 2015 Jan-Feb;60(1):46-50. doi: 10.4103/0019-5154.147789.

Neurotized congenital melanocytic nevus and pigmented neurofibroma (PNF) are close mimics and pose a clinicopathological challenge. We present a case of pigmented hypertrichotic plaque over lumbosacral region and discuss the differential diagnosis and its clinical, histopathological and immunohistochemistry features which may aid in differentiation. We highlight the difficulties faced in differentiating neurotized congenital melanocytic nevus from pigmented neurofibroma.

神经化先天性黑素细胞痣与色素性神经纤维瘤（PNF）极为相似，构成了临床病理诊断上的挑战。我们报告一例腰骶部色素沉着性多毛斑块病例，并讨论其鉴别诊断以及有助于鉴别的临床、组织病理学和免疫组化特征。我们着重强调了区分神经化先天性黑素细胞痣与色素性神经纤维瘤时所面临的困难。