Shen Qingyu, Rong Xiaoming, Pan Rui, Peng Ying, Peng Wei, Tang Yamei
Department of Neurology, Zengcheng People's Hospital, Zengcheng 511300, Guangdong Province, China.
Department of Neurology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, Guangdong Province, China.
Neural Regen Res. 2012 Jul 25;7(21):1675-9. doi: 10.3969/j.issn.1673-5374.2012.21.011.
This study examined a 24-year-old patient with delayed encephalopathy, who was admitted to hospital with complaints of headache and visual impairment 1 week after acute carbon monoxide poisoning. The results of a visual field assessment, electroencephalography and head magnetic resonance imaging indicated damage to the cerebral cortex. After a 2-week treatment period, the patient had recovered from the visual impairment, but exhibited digit- and letter-reading difficulty. The Chinese aphasia battery and the number and letter battery supplement were conducted. The results revealed that the patient exhibited digit and letter alexia, while the ability to read Chinese characters was preserved. In contrast, the patient exhibited a deficit in Chinese character writing, while number and letter writing remained intact. Following treatment, reading and writing ability was improved and electroencephalographic abnormalities were ameliorated. Overall, our experimental findings demonstrated that delayed encephalopathy following acute carbon monoxide poisoning was characterized by digit and letter alexia.
本研究对一名24岁的迟发性脑病患者进行了检查，该患者在急性一氧化碳中毒1周后因头痛和视力障碍入院。视野评估、脑电图和头部磁共振成像结果表明大脑皮层受损。经过2周的治疗期，患者的视力障碍已恢复，但出现数字和字母阅读困难。进行了汉语失语症成套测验和数字与字母成套补充测验。结果显示，患者存在数字和字母失读症，而汉字阅读能力保留。相反，患者在汉字书写方面存在缺陷，而数字和字母书写保持完好。经过治疗，阅读和书写能力得到改善，脑电图异常情况也有所改善。总体而言，我们的实验结果表明，急性一氧化碳中毒后的迟发性脑病以数字和字母失读症为特征。
