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右心室切开术后长期植入人工血管后猪的心血管血流动力学

Cardiovascular hemodynamics in the swine following long-term placement of prosthetic grafts post right ventriculotomy.

作者信息

Cissik J H, Ehler W J

机构信息

Clinical Investigations, Wilford Hall USAF Medical Center, Lackland AFB, TX 78236.

出版信息

Comp Biochem Physiol A Comp Physiol. 1989;92(3):327-30. doi: 10.1016/0300-9629(89)90572-0.

DOI:10.1016/0300-9629(89)90572-0
PMID:2565784
Abstract
  1. Heart rate, cardiac output and arterial, pulmonary artery, central venous and pulmonary wedge pressures were measured in eight neutered male pigs of an average of 14 months of age and 145.0-231.0 kg body weight. 2. These measurements were made 10-16 months after right ventriculotomy and placement of Gore-Tex PTFE Vascular Grafts. 3. Arithmetic means, standard deviations and coefficients of variation were calculated and the 95% confidence limits for ranges were established. 4. Comparison of derived data with that from published data on swine and on humans indicated normal cardiovascular hemodynamics in this group. 5. In addition, there was no gradient across the patched area. 6. It appears, therefore, that these patches had no adverse effects on the cardiovascular system of growing pigs.
摘要
  1. 对8只平均年龄14个月、体重145.0 - 231.0千克的去势雄性猪测量了心率、心输出量以及动脉压、肺动脉压、中心静脉压和肺楔压。2. 这些测量在右心室切开术及植入戈尔特斯聚四氟乙烯血管移植物10 - 16个月后进行。3. 计算了算术平均值、标准差和变异系数,并确定了范围的95%置信限。4. 将所得数据与已发表的猪和人类数据进行比较,表明该组心血管血液动力学正常。5. 此外,修补区域没有压力梯度。6. 因此,似乎这些补片对生长猪的心血管系统没有不良影响。

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