共轭聚合物纳米颗粒与合成尿液中糖胺聚糖的差异相互作用。
Differential interactions of conjugated polymer nanoparticles with glycosaminoglycans in synthetic urine.
作者信息
Twomey Megan, Vokatá Tereza, Kumar Manian Rajesh, Moon Joong Ho
机构信息
Biomolecular Sciences Institute, Department of Chemistry and Biochemistry, Florida International University, 11200 SW 8th St., Miami, FL 33199, USA.
出版信息
Chem Commun (Camb). 2015 Mar 7;51(19):4065-8. doi: 10.1039/c5cc00110b.
Abstract
Four different conjugated polymer nanoparticles (CPNs) were used to differentiate structurally similar glycosaminoglycans (GAGs) in a urine simulant. Unique emission response patterns of CPNs were analyzed by linear discriminant analysis (LDA), confirming that structurally diverse CPNs are sensitive and effective at differentiating GAGs in a complex biological medium.
摘要
四种不同的共轭聚合物纳米颗粒（CPNs）被用于区分尿液模拟物中结构相似的糖胺聚糖（GAGs）。通过线性判别分析（LDA）分析了CPNs独特的发射响应模式，证实结构多样的CPNs在复杂生物介质中区分GAGs时灵敏且有效。
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