Smith Dana, Stringer Elizabeth, Vladutiu Catherine J, Zink Ashley Hickman, Strauss Robert
Department of Obstetrics and Gynecology, School of Medicine, University of North Carolina, Chapel Hill, School of Medicine, Chapel Hill, NC.
Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, School of Medicine, Chapel Hill, NC.
Am J Obstet Gynecol. 2015 Jul;213(1):80.e1-80.e5. doi: 10.1016/j.ajog.2015.01.056. Epub 2015 Feb 4.
The purpose of this study was to estimate the association of uterine rupture and previous incision type, either unknown or low transverse, among women who attempt a trial of labor after 1 previous cesarean delivery.
We conducted a secondary analysis of a prospective multicenter observational study of 15,519 women with term singletons who attempted a trial of labor after 1 previous cesarean delivery. Odds ratios for the association between uterine incision location, either unknown or low transverse, and uterine rupture were estimated with the use of multivariable logistic regression.
Between 1999 and 2002, 99 of the 15,519 women (0.64%) who attempted a trial of labor after 1 previous cesarean delivery experienced a uterine rupture. Pregnant women with an unknown scar had lower odds of uterine rupture (adjusted odds ratio, 0.71; 95% confidence interval, 0.37-1.37) compared with women with a known low transverse scar. Other adverse maternal outcomes did not differ between the 2 groups of women.
Among this cohort, women with an unknown uterine incision who attempted a trial of labor were not at increased risk of uterine rupture compared with women with a known low transverse incision.
本研究旨在评估既往有一次剖宫产史且尝试经阴道分娩的女性中子宫破裂与既往切口类型(未知或低位横切口)之间的关联。
我们对一项前瞻性多中心观察性研究进行了二次分析,该研究纳入了15519名单胎足月且既往有一次剖宫产史并尝试经阴道分娩的女性。使用多变量逻辑回归估计子宫切口位置(未知或低位横切口)与子宫破裂之间关联的比值比。
在1999年至2002年期间,15519名既往有一次剖宫产史并尝试经阴道分娩的女性中有99名(0.64%)发生子宫破裂。与已知低位横切口的女性相比,瘢痕情况未知的孕妇发生子宫破裂的几率较低(校正比值比为0.71;95%置信区间为0.37 - 1.37)。两组女性的其他不良母儿结局无差异。
在该队列中,与已知低位横切口的女性相比,既往有一次剖宫产史且尝试经阴道分娩但子宫切口情况未知的女性发生子宫破裂的风险并未增加。