Witzsch U K F, Becht E
Klinik für Urologie und Kinderurologie, Krankenhaus Nordwest GmbH, Stiftung Hospital zum Heiligen Geist, Steinbacher Hohl 2-26, 60488, Frankfurt/Main, Deutschland,
Urologe A. 2015 Feb;54(2):191-201. doi: 10.1007/s00120-014-3667-1.
Due to continuous technical developments for more than 60 years followed by better clinical results with minimal side effects, cryoablation of the prostate for localized prostate cancer has evolved as a true alternative therapeutic option for selected patients.
The current form of cryoablation has almost nothing in common with those established in the 1960s and 1970s, which were further developed in the 1980s and 1990s. Nowadays it is a minimally invasively and highly effective treatment for high-risk carcinomas and failure of other therapeutic modalities.
Thus, cryoablation of the prostate is indicated if there are absolute or relative contraindications for radical surgery. In salvage cases for localized prostate cancer, cryoablation is the therapy of choice. Cryoablation is also an option for focal therapy. Standardization of the procedure, definition of freeze-thaw cycles, and structured training programs have led to this status.
经过60多年的持续技术发展，前列腺冷冻消融术治疗局限性前列腺癌取得了更好的临床效果且副作用最小，已成为特定患者真正的替代治疗选择。
当前形式的冷冻消融术与20世纪60年代和70年代确立的方法几乎没有共同之处，后者在20世纪80年代和90年代得到进一步发展。如今，它是治疗高危癌症和其他治疗方式失败的一种微创且高效的治疗方法。
因此，如果存在根治性手术的绝对或相对禁忌症，前列腺冷冻消融术是适用的。在局限性前列腺癌的挽救性治疗中，冷冻消融术是首选治疗方法。冷冻消融术也是局部治疗的一种选择。该手术的标准化、冻融周期的定义以及结构化培训项目促成了这种现状。
