Shellhaas Renée A
Department, Division of Pediatric Neurology, C.S. Mott Children's Hospital, University of Michigan Health System, Ann Arbor, MI, USA.
Semin Fetal Neonatal Med. 2015 Jun;20(3):149-53. doi: 10.1016/j.siny.2015.01.005. Epub 2015 Feb 7.
Newborn infants at risk for cerebral dysfunction, such as those with acute brain injury or with disorders of brain development, often have encephalopathy and seizures. Conventional electroencephalography (EEG) monitoring can enhance the care of these highly vulnerable patients, through identification of prognostically significant EEG background patterns and accurate diagnosis of seizures and non-seizure paroxysmal events. Neonatal seizures are usually subclinical, and abnormal neonatal movements are often not the result of seizures. Judicious use of conventional EEG monitoring can provide precise diagnosis, quantify seizures, and guide treatment--neonates with EEG-proven seizures should receive appropriate medications and those whose events are not seizures may be spared unnecessary exposure to medications that have potentially important side-effects.
有脑功能障碍风险的新生儿，如患有急性脑损伤或脑发育障碍的新生儿，常常会出现脑病和癫痫发作。传统脑电图（EEG）监测可通过识别具有预后意义的EEG背景模式以及准确诊断癫痫发作和非癫痫性阵发性事件，来加强对这些高危患者的护理。新生儿癫痫发作通常为亚临床发作，新生儿异常运动往往并非由癫痫发作所致。合理使用传统EEG监测能够提供精确诊断、量化癫痫发作并指导治疗——EEG证实有癫痫发作的新生儿应接受适当药物治疗，而那些发作并非由癫痫引起的新生儿则可避免不必要地接触具有潜在重要副作用的药物。
