视黄醇类和3,4-二脱氢视黄醇类在金鱼体内的分布。
Distribution of retinoids and 3,4-didehydroretinoids in the goldfish.
作者信息
Tsin Andrew T C, Morales Santiago T, Flores Janie M
机构信息
Division of Life Sciences, The University of Texas at San Antonio, San Antonio, TX, U.S.A. 78285.
出版信息
Can J Zool. 1986 Sep;64(9):2066-2067. doi: 10.1139/z86-313.
Using high-performance liquid chromatography, the quantity of retinol, retinal, and retinyl esters as well as their 3,4-didehydro derivatives were measured in several body compartments and in the remainder of the body of 11 goldfish. Eighty-six percent of these retinoids and 3,4-didehydroretinoids existed as retinyl and 3,4-didehydroretinyl 10% as retinal and 3,4-didehydroretinal, and 4% as retinol and 3,4-didehydroretinol. Most (94%) of these retinoids and 3,4-didehydroretinoids were found in ocular tissues and high ratios of 3,4-didehydroretinoids/retinoids were observed in most tissue extracts. These data suggest that in the goldfish ocular tissues are important locations of retinoid and 3,4-didehydroretinoid metabolism, which favors the formation and (or) storage of 3,4-didehydroretinoids.
采用高效液相色谱法，测定了11条金鱼多个身体部位及鱼体其他部分中视黄醇、视黄醛、视黄酯及其3,4 - 二脱氢衍生物的含量。这些类视黄醇和3,4 - 二脱氢类视黄醇中，86%以视黄酯和3,4 - 二脱氢视黄酯的形式存在，10%以视黄醛和3,4 - 二脱氢视黄醛的形式存在，4%以视黄醇和3,4 - 二脱氢视黄醇的形式存在。这些类视黄醇和3,4 - 二脱氢类视黄醇大部分（94%）存在于眼部组织中，并且在大多数组织提取物中观察到较高的3,4 - 二脱氢类视黄醇/类视黄醇比例。这些数据表明，在金鱼中，眼部组织是类视黄醇和3,4 - 二脱氢类视黄醇代谢的重要部位，有利于3,4 - 二脱氢类视黄醇的形成和（或）储存。
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