蚁毒中的激肽——与相关膜翅目昆虫毒液的比较。

Kinins in ant venoms--a comparison with venoms of related Hymenoptera.

Piek T, Schmidt J O, de Jong J M, Mantel P

Department of Pharmacology, University of Amsterdam, The Netherlands.

Comp Biochem Physiol C Comp Pharmacol Toxicol. 1989;92(1):117-24. doi: 10.1016/0742-8413(89)90212-0.

Abstract

Venom preparations have been made of six ant, one pompilid wasp, two mutillid wasp, and four social wasp species. 2. The venoms were analysed pharmacologically in order to detect kinin-like activity. 3. Due to the small amounts of venoms available only a cascade of smooth muscle preparation could be used. 4. Kinin activities have been found in five ant venoms and in four social wasp venoms. 5. No kinin activity has been found in the venoms of the pompilid and mutillid wasps. 6. All ant venoms also contain unidentified agonists for vertebrate smooth muscle preparations.

摘要

已从六种蚂蚁、一种蛛蜂、两种蚁蜂和四种胡蜂中制备了毒液制剂。2. 对毒液进行了药理学分析，以检测类激肽活性。3. 由于可用毒液量少，仅能使用平滑肌制备的级联反应。4. 在五种蚂蚁毒液和四种胡蜂毒液中发现了激肽活性。5. 在蛛蜂和蚁蜂的毒液中未发现激肽活性。6. 所有蚂蚁毒液还含有对脊椎动物平滑肌制剂未鉴定的激动剂。