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Effects of tributyltin compounds on ionic regulation and gill ATPase activity in estuarine fish.

作者信息

Pinkney A E, Wright D A, Jepson M A, Towle D W

机构信息

University of Maryland, Center for Environmental & Estuarine Studies, Chesapeake Biological Laboratory, Solomons 20688.

出版信息

Comp Biochem Physiol C Comp Pharmacol Toxicol. 1989;92(1):125-9. doi: 10.1016/0742-8413(89)90213-2.

DOI:10.1016/0742-8413(89)90213-2
PMID:2566432
Abstract
  1. Striped bass (Morone saxatilis) were exposed to 0, 0.10, 0.34, or 1.09 micrograms/l tributyltin (TBT) for 14 days. Gill Mg2+ ATPase and serum Na+, K+, Ca2+ and Mg2+ were not altered. Na+K+ATPase was significantly (P less than 0.05) increased (+48%) at 0.10 microgram/l. 2. In striped bass gill homogenates exposed to TBT in vitro, there was significant inhibition of Na+K+ATPase at 106.0 micrograms/l (17.2%) and Mg2+ATPase at 53.0 and 106.0 micrograms/l (16.0% and 24.3%, respectively). 3. In mummichog (Fundulus heteroclitus) gill homogenates, there was significant inhibition of Na+K+ATPase at 25.3 and 50.5 micrograms/l (10.9% and 16.1%) and Mg2+ATPase at 5.1, 25.3, and 50.5 micrograms/l (26.7%, 32.2%, and 36.2%).
摘要

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