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睾酮作为改变埃卡廷对法老鹌鹑(Coturnix coturnix Pharaoh)毒性的一个因素。I. 成年鸟。

Testosterone as a factor modifying the toxicity of ekatin for the Pharaoh quail (Coturnix coturnix Pharaoh). I. Mature birds.

作者信息

Gromysz-Kałkowska K, Szubartowska E, Kaczanowska E

机构信息

Department of Animal Physiology, Maria Curie-Skłodowska University, Lublin, Poland.

出版信息

Comp Biochem Physiol C Comp Pharmacol Toxicol. 1989;92(1):89-93. doi: 10.1016/0742-8413(89)90208-9.

Abstract
  1. Testosterone reduces the haemolytic action of Ekatin on the morphotic blood elements by accelerating maturation of erythroblastic cells. 2. Testosterone, by accelerating the metabolism of the pesticide causes a defective defence processes of the organism by decreasing the number of macrophages. 3. Intoxication of androgenised birds with Ekatin leads to a breakdown of the systemic adaptive mechanisms by rapid and early switching on the adrenal cortex in response to the stress caused by poisoning.
摘要
  1. 睾酮通过加速成红细胞的成熟来降低埃卡廷对形态学血液成分的溶血作用。2. 睾酮通过加速农药的代谢,减少巨噬细胞数量,从而导致机体防御过程出现缺陷。3. 用埃卡廷对雄激素化的鸟类进行中毒处理,会导致全身适应性机制的崩溃,因为中毒引起的应激会使肾上腺皮质迅速且提前启动。

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