Su Ji, Liu Huixin, Hua Ruimao
Department of Chemistry, Tsinghua University, Beijing 100084, China.
National Engineering Laboratory for Rice and Byproduct Deep Processing, Central South University of Forestry and Technology, Changsha 410004, China.
Int J Mol Sci. 2015 Feb 5;16(2):3599-608. doi: 10.3390/ijms16023599.
3-Substituted 2,5-dimethylpyrazines were synthesized in high yields via a one-pot cascade annulation of easily available propargyl amine with aldehydes catalyzed by Au(PPh2Cy)Cl.
通过金(二苯基环戊基膦)氯催化易得的炔丙胺与醛的一锅串联环化反应,以高产率合成了3-取代的2,5-二甲基吡嗪。