Gitnick G
School of Medicine, Los Angeles, California 90024.
J Int Med Res. 1989;17 Suppl 1:17A-24A.
Since its introduction into the USA, famotidine has been widely studied. A variety of studies has shown it to be a very potent H2-receptor antagonist; more potent and longer acting than cimetidine or ranitidine. It has been shown to be efficacious, cost-effective and relatively safe in the treatment of duodenal ulcers, benign gastric ulcers, in maintenance therapy, and when used intravenously in the critical care setting.
自法莫替丁引入美国以来,已得到广泛研究。多项研究表明它是一种非常强效的H2受体拮抗剂;比西咪替丁或雷尼替丁更有效且作用时间更长。已证明它在治疗十二指肠溃疡、良性胃溃疡、维持治疗以及在重症监护环境中静脉使用时有效、具有成本效益且相对安全。