Ales K L, Santini D L
Department of Medicine, New York Hospital, Cornell University Medical Center.
Lancet. 1989 May 27;1(8648):1187-91. doi: 10.1016/s0140-6736(89)92763-3.
Although gestational glucose intolerance is associated with the remote development of diabetes mellitus, the risk to the mother during the index pregnancy and the risk to her fetus remain uncertain. Nevertheless, universal screening for gestational glucose intolerance has many strong advocates. The scientific data supporting a universal screening programme--showing that treatment of gestational glucose intolerance does more good than harm--are limited. Until the evidence can be extended beyond that on infant birthweight, a more restrained approach than universal screening may be appropriate.
尽管妊娠期糖耐量异常与远期糖尿病的发生有关,但在本次妊娠期间对母亲的风险以及对胎儿的风险仍不明确。然而,仍有许多人大力主张对妊娠期糖耐量异常进行普遍筛查。支持普遍筛查方案的科学数据——表明治疗妊娠期糖耐量异常利大于弊——很有限。在证据能够扩展到婴儿出生体重以外的情况之前,采取比普遍筛查更为谨慎的方法可能更为合适。